Hamonari Nasreen Hamarash
Dental Public Health, Kurdistan Higher Council of Medical Specialists, Erbil, IRQ.
Cureus. 2024 Aug 12;16(8):e66675. doi: 10.7759/cureus.66675. eCollection 2024 Aug.
Aloe vera has gained significant attention in clinical research, and promoting natural substances is a prevailing trend in dentistry.
This study compares the effectiveness of aloe vera mouthwash and 0.2% chlorhexidine gluconate mouthwash in reducing plaque accumulation and gingivitis.
A single-masked trial included 270 volunteers who were systemically healthy and aged between 18 and 45 years. The participants were randomly assigned to three groups: Group A (the test group) received aloe vera mouth rinse, Group B (the positive control group) received a placebo (distilled water), and Group C (the negative control group) received 0.2% chlorhexidine. Clinical indicators, which include the plaque index (PI) by Sillness and Loe in 1964 and the gingival index (GI) by Loe and Sillness in 1963, were evaluated at baseline, day 15, and day 30 for all three groups. Participants were directed to rinse their mouths with the specified mouthwash twice daily for 30 days.
Significant reductions in the GI and PI were observed in both aloe vera and chlorhexidine mouthwashes, with a statistical significance of p<0.001. The placebo mouthwash also showed reductions in both the GI and PI, with a significance level of p<0.001. Post hoc analysis revealed no significant differences between the aloe vera and chlorhexidine groups for the GI and PI, with p-values of 0.6 and 0.8, respectively.
Aloe vera has proven equally effective as chlorhexidine in reducing plaque and gingivitis. This makes it a viable alternative for treating and preventing gingivitis, appealing to those preferring natural, holistic oral care. Incorporating aloe vera mouthwash into daily routines offers an effective, natural solution for maintaining gum health.
芦荟在临床研究中受到了广泛关注，推广天然物质是牙科领域的一个流行趋势。
本研究比较芦荟漱口水和0.2%葡萄糖酸氯己定漱口水在减少牙菌斑积聚和牙龈炎方面的效果。
一项单盲试验纳入了270名全身健康、年龄在18至45岁之间的志愿者。参与者被随机分为三组：A组（试验组）使用芦荟漱口水，B组（阳性对照组）使用安慰剂（蒸馏水），C组（阴性对照组）使用0.2%葡萄糖酸氯己定。在基线、第15天和第30天对所有三组进行临床指标评估，包括1964年Sillness和Loe提出的菌斑指数（PI）以及1963年Loe和Sillness提出的牙龈指数（GI）。参与者被要求每天用指定的漱口水漱口两次，持续30天。
芦荟漱口水和氯己定漱口水的GI和PI均显著降低，p<0.001，具有统计学意义。安慰剂漱口水的GI和PI也有所降低，显著性水平为p<0.001。事后分析显示，芦荟组和氯己定组在GI和PI方面无显著差异，p值分别为0.6和0.8。
芦荟在减少牙菌斑和牙龈炎方面已被证明与氯己定同样有效。这使其成为治疗和预防牙龈炎的可行替代方法，对那些倾向于天然、整体口腔护理的人具有吸引力。将芦荟漱口水纳入日常护理为保持牙龈健康提供了一种有效、天然的解决方案。
