不成熟血小板分数可作为儿童 2019 年呼吸道冠状病毒疾病严重程度的生物标志物。
Immature Platelet Fraction as a Biomarker for Disease Severity in Pediatric Respiratory Coronavirus Disease 2019.
机构信息
Departments of Internal Medicine and Pediatrics, University of Texas Southwestern, Dallas, TX.
School of Data Science, University of North Carolina at Charlotte, Charlotte, NC.
出版信息
J Pediatr. 2022 Dec;251:187-189. doi: 10.1016/j.jpeds.2022.07.035. Epub 2022 Aug 6.
Abstract
In this retrospective single-institution cohort study of 113 hospitalized pediatric patients with respiratory coronavirus disease 2019, those admitted to the intensive care unit or requiring mechanical ventilation had significantly higher immature platelet fractions than those who did not require intensive care unit-level care or ventilation. Immature platelet fraction may be an accessible biomarker for disease severity in pediatric respiratory coronavirus disease 2019.
摘要
在这项回顾性单机构队列研究中，纳入了 113 例住院的儿科 2019 冠状病毒病患者，与不需要重症监护或通气的患者相比，需要入住重症监护病房或需要机械通气的患者血小板未成熟分数明显更高。血小板未成熟分数可能是儿科 2019 冠状病毒病严重程度的一种易于获取的生物标志物。
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