Lefkowitz S S, Klager K
Immunol Commun. 1978;7(5):557-66. doi: 10.3109/08820137809025484.
The effects of delta9-tetrahydrocannabinol (delta9-THC) on the immune response of murine cells sensitized in vitro was determined using a plaque-forming cell (PFC) assay. Splenic lymphocytes from mice injected with delta9-THC showed a depressed immunologic response when compared with cells from control animals which were identically sensitized in vitro with sheep erythrocytes (SRBC). The direct addition of delta9-THC to the culture media altered the immunological response as demonstrated by a reduction in the number of PFC.
使用空斑形成细胞（PFC）试验测定了δ9-四氢大麻酚（δ9-THC）对体外致敏的小鼠细胞免疫反应的影响。与用绵羊红细胞（SRBC）在体外进行相同致敏的对照动物的细胞相比，注射了δ9-THC的小鼠的脾淋巴细胞显示出免疫反应受到抑制。如PFC数量减少所示，将δ9-THC直接添加到培养基中会改变免疫反应。
