J Refract Surg. 2022 Aug;38(8):538-546. doi: 10.3928/1081597X-20220707-01. Epub 2022 Aug 1.
To compare different outcomes of an enhanced monofocal intraocular lens (IOL) versus a conventional monofocal IOL implantation after cataract surgery.
The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guideline was used for abstracting data and assessing quality. Comparative studies between enhanced monofocal versus conventional monofocal IOL implantations reporting outcomes in monocular and binocular visual acuities at various distances, spectacle independence, contrast sensitivity, optical quality, and adverse effects were identified from three databases. Meta-analysis, sensitivity analysis, and subgroup analysis were performed.
A total of 680 eyes implanted with an enhanced monofocal IOL (Tecnis Eyhance ICB00; Johnson & Johnson) and 647 eyes with a conventional monofocal IOL from 3 randomized controlled trials and 9 comparative studies were included. The enhanced monofocal IOL showed better monocular uncorrected intermediate visual acuity (UIVA) (mean difference [MD]: -0.11 logMAR; 95% CI: -0.12 to -0.09), binocular UIVA (MD: -0.17 logMAR; 95% CI: -0.23 to -0.11), and binocular uncorrected near visual acuity performance (MD: -0.17 logMAR; 95% CI: -0.29 to -0.04) than the conventional monofocal IOL. More patients were spectacle free at intermediate distance with the enhanced monofocal IOL (odds ratio: 12.9; 95% CI: 6.2 to 27.0). Both monocular (MD: -0.002 logMAR; 95% CI: -0.01 to 0.01) and binocular (MD: 0.01 logMAR; 95% CI: -0.02 to 0.03) uncorrected distance visual acuity revealed non-significant differences between the IOL designs. Contrast sensitivity, photic phenomenon, and adverse effects were comparable.
Enhanced monofocal IOLs effectively improved unaided intermediate vision with similar distance performance relative to conventional monofocal IOLs. This was achieved without compromising the contrast sensitivity or inducing photic phenomena. .
比较增强型单焦点人工晶状体（IOL）与常规单焦点 IOL 白内障手术后的不同结果。
使用系统评价和荟萃分析（PRISMA）首选报告项目来提取数据和评估质量。从三个数据库中确定了比较增强型单焦点与常规单焦点 IOL 植入术的研究，这些研究报告了单眼和双眼在不同距离的视力、离焦独立、对比敏感度、光学质量和不良反应。进行了荟萃分析、敏感性分析和亚组分析。
共有 680 只眼植入增强型单焦点 IOL（Tecnis Eyhance ICB00；Johnson & Johnson），647 只眼植入常规单焦点 IOL，来自 3 项随机对照试验和 9 项比较研究。增强型单焦点 IOL 在单眼未矫正中间视力（UIVA）（平均差异 [MD]：-0.11 logMAR；95%CI：-0.12 至-0.09）、双眼 UIVA（MD：-0.17 logMAR；95%CI：-0.23 至-0.11）和双眼未矫正近视力表现（MD：-0.17 logMAR；95%CI：-0.29 至-0.04）方面均优于常规单焦点 IOL。更多的患者在中距离无需戴眼镜，增强型单焦点 IOL 的无眼镜率为 12.9（95%CI：6.2 至 27.0）。单眼（MD：-0.002 logMAR；95%CI：-0.01 至 0.01）和双眼（MD：0.01 logMAR；95%CI：-0.02 至 0.03）未矫正距离视力无显著差异。对比敏感度、光幻视和不良反应相当。
与常规单焦点 IOL 相比，增强型单焦点 IOL 可有效改善未经矫正的中间视力，同时保持类似的远距离视力。这是在不影响对比敏感度或引起光幻视的情况下实现的。
