Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Talent Anxiety Service, Center of Hunan Provincial Health Commission, Changsha, China.
Support Care Cancer. 2022 Nov;30(11):9453-9460. doi: 10.1007/s00520-022-07318-6. Epub 2022 Aug 10.
To study the level of fear of cancer recurrence (FCR) in patients receiving surgery for non-small cell lung cancer (NSCLC) and explore related factors that can increase levels of hope in this population, enhance the confidence to defeat the disease, and thus increase the quality of life.
A total of 327 postoperative NSCLC patients from the National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College were enrolled. All participants completed the General Questionnaire, Fear of Progression Questionnaire-Short Form (FoP-Q-SF), Herth Hope Index (HHI) Scale, and Social Support Rating Scale (SSRS).
The mean FoP-Q-SF score was (30.3 ± 9.48) points in postoperative NSCLC patients, Among them, there were 188 patients (57.5%) who had psychological dysfunction, indicated by a score of > / = 34. Patient sex and family income were independent risk factors for FCR (both p < 0.05). Correlation analysis revealed a negative association between FCR and hope level (p < 0.05) and a positive association between hope level and social support (p < 0.05). Notably, social support mediated the association between FCR and hope in patients receiving surgery for NSCLC (contribution effect: 30.24%).
Postoperative NSCLC patients experience a moderate level of FCR, especially females and those with a low family income. Social support partially mediates the relationship between FCR and hope in this population. Therefore, an increase in the level of social support can increase hope among these patients and advancing recovery.
研究非小细胞肺癌（NSCLC）术后患者的癌症复发恐惧（FCR）水平，探讨能够增加该人群希望水平的相关因素，增强战胜疾病的信心，从而提高生活质量。
共纳入中国医学科学院肿瘤医院国家癌症中心/国家肿瘤临床医学研究中心/北京协和医学院 327 例 NSCLC 术后患者。所有参与者均完成一般问卷、进展恐惧问卷-短表（FoP-Q-SF）、Herth 希望指数（HHI）量表和社会支持评定量表（SSRS）。
NSCLC 术后患者 FoP-Q-SF 评分为（30.3±9.48）分，其中 188 例（57.5%）患者存在心理功能障碍，评分≥34 分。患者性别和家庭收入是 FCR 的独立危险因素（均 P＜0.05）。相关性分析显示，FCR 与希望水平呈负相关（P＜0.05），与社会支持呈正相关（P＜0.05）。社会支持在 NSCLC 术后患者 FCR 与希望之间起部分中介作用（贡献效应：30.24%）。
NSCLC 术后患者存在中等程度的 FCR，尤其是女性和家庭收入较低的患者。社会支持部分中介 FCR 与希望之间的关系。因此，增加社会支持水平可以增加这些患者的希望，促进康复。
