Liu Man, Liu Lu, Lv Zhuoheng, Zeng Qingpeng, Zhao Jun
National Cancer Center/National Clinical Research Center for Cancer (NCRCC)/Thoracic Surgery, Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Asia Pac J Oncol Nurs. 2025 Feb 10;12:100663. doi: 10.1016/j.apjon.2025.100663. eCollection 2025 Dec.
This study aimed to identify latent profiles of fear of cancer recurrence (FCR) among patients with early-stage non-small cell lung cancer (NSCLC) and examine the associated factors.
A cross-sectional survey was conducted with 677 patients with early-stage NSCLC who underwent surgical treatment at a tier-three cancer hospital in Beijing between January 2022 and August 2023. Data collection included demographic variables and assessments using the Fear of Progression Questionnaire-Short Form (FoP-Q-SF), Herth Hope Index (HHI), and Social Support Rating Scale (SSRS). Latent profile analysis was employed to classify FCR levels and identify influencing factors.
Three distinct FCR profiles emerged: "low FCR" (27.6%), "moderate FCR" (66.2%), and "high FCR" (6.2%). Independent risk factors for moderate FCR included individuals aged 36-60 years (odds ratio [OR] = 1.871, 95% confidence interval [CI] 1.208-2.899) and a household income below 5000 yuan (OR = 1.86, 95% CI 1.059-3.267). Protective factors for moderate FCR included lower levels of education (OR = 0.505, 95% CI 0.283-0.902), religious beliefs (OR = 0.355, 95% CI 0.152-0.833), and smoking (OR = 0.461, 95% CI 0.284-0.747). High FCR was strongly associated with being 36-60 years old, lower HHI scores (OR = 11.055, 95% CI 4.441-27.522), and poor social support (OR = 3.392, 95% CI 1.385-8.308).
FCR among patients with early-stage NSCLC can be categorized into distinct profiles, with specific demographic and psychosocial factors influencing severity. Tailored nursing interventions addressing varying FCR levels are critical to improving patient care and psychological well-being.
本研究旨在识别早期非小细胞肺癌（NSCLC）患者中癌症复发恐惧（FCR）的潜在特征，并探讨相关因素。
对2022年1月至2023年8月间在北京一家三级癌症医院接受手术治疗的677例早期NSCLC患者进行了横断面调查。数据收集包括人口统计学变量，以及使用癌症进展恐惧问卷简表（FoP-Q-SF）、赫思希望指数（HHI）和社会支持评定量表（SSRS）进行的评估。采用潜在特征分析来分类FCR水平并确定影响因素。
出现了三种不同的FCR特征：“低FCR”（27.6%）、“中度FCR”（66.2%）和“高FCR”（6.2%）。中度FCR的独立危险因素包括年龄36至60岁的个体（比值比[OR]=1.871，95%置信区间[CI]1.208 - 2.899）和家庭收入低于5000元（OR = 1.86，95% CI 1.059 - 3.267）。中度FCR的保护因素包括较低的教育水平（OR = 0.505，95% CI 0.283 - 0.902）、宗教信仰（OR = 0.355，95% CI 0.152 - 0.833）和吸烟（OR = 0.461，95% CI 0.284 - 0.747）。高FCR与年龄36至60岁、较低的HHI得分（OR = 11.055，95% CI 4.441 - 27.522）以及较差的社会支持（OR = 3.392，95% CI 1.385 - 8.308）密切相关。
早期NSCLC患者的FCR可分为不同特征，特定的人口统计学和心理社会因素会影响其严重程度。针对不同FCR水平制定个性化护理干预措施对于改善患者护理和心理健康至关重要。
