Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear and Harvard Medical School, Boston, Massachusetts, USA.
Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Mov Disord. 2022 Sep;37(9):1798-1802. doi: 10.1002/mds.29178. Epub 2022 Aug 10.
Task-specificity in isolated focal dystonias is a powerful feature that may successfully be targeted with therapeutic brain-computer interfaces. While performing a symptomatic task, the patient actively modulates momentary brain activity (disorder signature) to match activity during an asymptomatic task (target signature), which is expected to translate into symptom reduction.
孤立性局灶性肌张力障碍的任务特异性是一个强大的特征,可能会成功地成为治疗性脑机接口的目标。在执行症状性任务时,患者主动调节瞬时脑活动(紊乱特征)以匹配无症状性任务期间的活动(目标特征),预计这将转化为症状减轻。