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收缩期震颤杂音的可能病因。

The possible etiology of the vibratory systolic murmur.

作者信息

Darazs B, Hesdorffer C S, Butterworth A M, Ziady F

出版信息

Clin Cardiol. 1987 May;10(5):341-6. doi: 10.1002/clc.4960100509.

Abstract

Between January and September 1985, 476 patients underwent two-dimensional and M-mode echocardiography. Left ventricular bands were noted in 104 of these individuals. Of these patients, 89 (85.6%) were referred for evaluation of a systolic murmur. In view of this high incidence of association between left ventricular bands and systolic murmurs, we decided to perform a prospective analysis on patients with the classical vibratory systolic murmur (Still's murmur) which is commonly found in children and young adults. The incidence of left ventricular bands would be compared with a group of individuals in whom no cardiac murmurs could be detected. It was hoped in this way to possibly determine whether there was a definite relationship between the vibratory systolic murmur and left ventricular bands. Echocardiographs were performed using an Advanced Technical Laboratories machine and gain settings were adjusted such that all artefacts and normal structures could easily be distinguished from the ventricular bands. The ventricular bands were divided into two types. Of significance, we felt, were those which crossed the left ventricular outflow tract and which could therefore have been responsible for the production of turbulence and thus a murmur reminiscent of the Still's murmur. This type of left ventricular band was noted in 76% of our patients with Still's murmurs as opposed to only 14% of the individuals without any murmur (p less than 0.001). This statistically significant difference led us to conclude that left ventricular bands might be the cause of the Still's murmur. Further investigation, particularly with Doppler studies would be required to confirm this interesting association.

摘要

1985年1月至9月期间,476例患者接受了二维和M型超声心动图检查。其中104例发现有左心室条带。在这些患者中,89例(85.6%)因收缩期杂音而转诊评估。鉴于左心室条带与收缩期杂音之间的高关联发生率,我们决定对儿童和年轻人中常见的典型振动性收缩期杂音(史迪尔杂音)患者进行前瞻性分析。将左心室条带的发生率与一组未检测到心脏杂音的个体进行比较。希望以此方式确定振动性收缩期杂音与左心室条带之间是否存在明确关系。使用先进技术实验室的机器进行超声心动图检查,并调整增益设置,以便所有伪像和正常结构都能容易地与心室条带区分开来。心室条带分为两种类型。我们认为重要的是那些穿过左心室流出道的条带,因此可能是产生湍流的原因,从而产生类似史迪尔杂音的杂音。在我们患有史迪尔杂音的患者中,76%发现了这种类型的左心室条带,而在无杂音的个体中仅为14%(p小于0.001)。这一具有统计学意义的差异使我们得出结论,左心室条带可能是史迪尔杂音的原因。需要进一步研究,特别是多普勒研究来证实这种有趣的关联。

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