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一名患有克罗恩病的儿科患者的憩室病,酷似阑尾切除术后阑尾残端穿孔。

Diverticular disease in a pediatric patient with Crohn's disease mimicking a perforated post-appendectomy appendiceal stump.

作者信息

de Nanassy Joseph, Mack David, Bettolli Marcos, Sergi Consolato M

机构信息

Department of Pathology, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada.

Department of Pediatric Gastroenterology, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada.

出版信息

J Surg Case Rep. 2022 Aug 5;2022(8):rjac355. doi: 10.1093/jscr/rjac355. eCollection 2022 Aug.

DOI:10.1093/jscr/rjac355
PMID:35949643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9359704/
Abstract

We present the finding of a diverticulum in the colonic wall of the cecum, arising in the context of ileocecal stricture in a child with Crohn disease mimicking a post-appendectomy perforated appendiceal stump. To our knowledge, a non-Meckel diverticulum in a pediatric patient with Crohn disease has not yet been reported and we examine the mechanics behind it. According to the Laplace Law, the pressure inside a container with curved walls is inversely proportional to its radius. A diverticulum forms at the point of maximum stricture and at the locus of least resistance (weakness) in the bowel wall due to the inflammatory bowel disease. The long-time interval between diagnosis of ileocecal stricture and surgery (9 months) is important to allow the formation of this diverticulum. Continued follow-up in adulthood is warranted due to an increased risk of intestinal diverticular disease and neoplasms in patients with Crohn disease.

摘要

我们报告了一名患有克罗恩病的儿童,在回盲部狭窄的情况下,盲肠结肠壁出现憩室,其表现类似阑尾切除术后穿孔的阑尾残端。据我们所知,尚未有关于小儿克罗恩病患者出现非梅克尔憩室的报道,我们对其背后的机制进行了研究。根据拉普拉斯定律,具有弯曲壁的容器内部压力与其半径成反比。由于炎症性肠病,憩室在肠壁最狭窄点和阻力最小(薄弱)部位形成。回盲部狭窄诊断与手术之间的长时间间隔(9个月)对该憩室的形成很重要。由于克罗恩病患者发生肠道憩室病和肿瘤的风险增加,因此成年后需要持续随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb77/9359704/9de713519984/rjac355f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb77/9359704/9de713519984/rjac355f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb77/9359704/9de713519984/rjac355f1.jpg

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Diverticular disease in a pediatric patient with Crohn's disease mimicking a perforated post-appendectomy appendiceal stump.一名患有克罗恩病的儿科患者的憩室病,酷似阑尾切除术后阑尾残端穿孔。
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本文引用的文献

1
Multiple Small Bowel Diverticula Were an Unexpected Finding During Laparoscopic Enterectomy for Crohn's Disease.腹腔镜回肠切除术治疗克罗恩病时,多发性小肠憩室是一个意外发现。
Med Arch. 2020 Apr;74(2):142-145. doi: 10.5455/medarh.2020.74.142-145.
2
Rare Coexistance of Ileal Diverticulosis, Crohn's Disease and Small Bowel Adenocarcinoma: Report of a Case.回肠憩室病、克罗恩病和小肠腺癌罕见并存:一例报告
In Vivo. 2018 Jan-Feb;32(1):191-195. doi: 10.21873/invivo.11224.
3
Role of visceral fat in colonic inflammation: from Crohn's disease to diverticulitis.
内脏脂肪在结肠炎症中的作用:从克罗恩病到憩室炎
Curr Opin Gastroenterol. 2017 Jan;33(1):53-58. doi: 10.1097/MOG.0000000000000324.
4
Increased Epithelial Gap Density in the Noninflamed Duodenum of Children With Inflammatory Bowel Diseases.炎症性肠病患儿非炎症十二指肠上皮间隙密度增加。
J Pediatr Gastroenterol Nutr. 2016 Dec;63(6):644-650. doi: 10.1097/MPG.0000000000001182.
5
Mucosal Barrier Depletion and Loss of Bacterial Diversity are Primary Abnormalities in Paediatric Ulcerative Colitis.黏膜屏障耗竭和细菌多样性丧失是儿童溃疡性结肠炎的主要异常表现。
J Crohns Colitis. 2016 Apr;10(4):462-71. doi: 10.1093/ecco-jcc/jjv223. Epub 2015 Dec 9.
6
Small bowel adenocarcinoma: epidemiology, risk factors, diagnosis and treatment.小肠腺癌:流行病学、危险因素、诊断与治疗。
Dig Liver Dis. 2014 Feb;46(2):97-104. doi: 10.1016/j.dld.2013.04.013. Epub 2013 Jun 21.
7
LaPlace's law revisited: cecal perforation as an unusual presentation of pancreatic carcinoma.再探拉普拉斯定律:盲肠穿孔作为胰腺癌的一种罕见表现
World J Surg Oncol. 2007 Feb 2;5:14. doi: 10.1186/1477-7819-5-14.
8
Crohn's-like reaction in diverticular disease.憩室病中的克罗恩样反应。
Gut. 1998 Mar;42(3):392-5. doi: 10.1136/gut.42.3.392.
9
Morphometry of the small intestine in pigs with ileo-rectal anastomosis.回肠直肠吻合术猪小肠的形态测量学
Can J Vet Res. 1997 Jan;61(1):21-7.