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肝移植患者社会经济状况及其他影响患者-移植物存活因素的分析

Analysis of socioeconomic status and other factors affecting patient-graft survival in patients undergoing liver transplantation.

作者信息

Onder Arif Hakan, Bengi Goksel, Ozbilgin Mucahit, Unek Tarkan, Astarcioglu Ibrahim, Akarsu Mesut

机构信息

Department of Internal Medicine, Dokuz Eylul University, Izmir, Turke.

Division of Gastroenterology, Department of Internal Medicine, Dokuz Eylul University, Izmir, Turkey.

出版信息

Hepatol Forum. 2020 Jan 20;1(1):25-36. doi: 10.14744/hf.2020.0003. eCollection 2020 Jan.

Abstract

BACKGROUND AND AIM

Liver transplantation is performed in increasing numbers due to advances in surgical techniques and the introduction of diverse immunosuppressive drugs. The present study aims to analyze the effects of socioeconomic status and education level on patient and graft survival, in addition to all these factors.

MATERIAL AND METHODS

All patients aged 18 years and above who underwent consecutive liver transplantation at the Liver Transplantation Unit of Department of General Surgery at the Dokuz Eylül University Hospital and whose data were available were included in this study.

RESULTS

Incompliance was noted in 68.3% of the 278 patients. On the other hand, patient compliance did not have a significant effect on graft and patient survival. However, decreased levels in the parameters, such as education status, vocational status and socioeconomic status, were found to be correlated with patient compliance. A significant correlation was not found between these factors and patient and graft survival.

CONCLUSION

Although a direct effect of socioeconomic status on patient and graft survival could not be shown the significant association of vocational status and education status which determine socioeconomic level with parameters other than patient and graft survival may affect the success of liver transplants.

摘要

背景与目的

由于手术技术的进步以及多种免疫抑制药物的引入,肝移植的实施数量不断增加。本研究旨在除分析所有这些因素外,还分析社会经济地位和教育水平对患者及移植物存活的影响。

材料与方法

本研究纳入了所有年龄在18岁及以上、在多库兹艾吕尔大学医院普通外科肝移植科接受连续肝移植且数据可用的患者。

结果

278例患者中68.3%存在不依从情况。另一方面,患者依从性对移植物和患者存活没有显著影响。然而,发现教育状况、职业状况和社会经济状况等参数水平的降低与患者依从性相关。这些因素与患者及移植物存活之间未发现显著相关性。

结论

尽管未显示社会经济地位对患者及移植物存活有直接影响,但决定社会经济水平的职业状况和教育状况与患者及移植物存活以外的参数之间的显著关联可能会影响肝移植的成功率。

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