School of Chemical Engineering, Yeungnam University, Gyeongsan, 38541, Gyeongbuk, South Korea.
Polymers and pigments department, Chemical industries research institute, National Research Centre, El-Bohouth St, Dokki, Cairo, 12622, Egypt.
Top Curr Chem (Cham). 2022 Aug 11;380(5):45. doi: 10.1007/s41061-022-00395-5.
Glycopolymer materials have emerged as a significant biopolymer class that has piqued the scientific community's attention due to their potential applications. Recently, they have been found to be a unique synthetic biomaterial; glycopolymer materials have also been used for various applications, including direct therapeutic methods, medical adhesives, drug/gene delivery systems, and biosensor applications. Therefore, for the next stage of biomaterial research, it is essential to understand current breakthroughs in glycopolymer-based materials research. This review discusses the most widely utilized synthetic methodologies for glycopolymer-based materials, their properties based on structure-function interactions, and the significance of these materials in biosensing applications, among other topics. When creating glycopolymer materials, contemporary polymerization methods allow precise control over molecular weight, molecular weight distribution, chemical activity, and polymer architecture. This review concludes with a discussion of the challenges and complexities of glycopolymer-based biosensors, in addition to their potential applications in the future.
糖聚合物材料作为一类具有重要意义的生物聚合物，已经引起了科学界的关注，因为它们具有潜在的应用价值。最近，人们发现糖聚合物材料是一种独特的合成生物材料，已经被用于各种应用，包括直接治疗方法、医用粘合剂、药物/基因传递系统和生物传感器应用。因此，对于下一阶段的生物材料研究，了解基于糖聚合物的材料研究的最新突破至关重要。本文综述了基于糖聚合物的材料最广泛使用的合成方法学、基于结构-功能相互作用的性质，以及这些材料在生物传感应用中的重要性等主题。在合成糖聚合物材料时，现代聚合方法可以精确控制分子量、分子量分布、化学活性和聚合物结构。本文最后讨论了基于糖聚合物的生物传感器的挑战和复杂性，以及它们在未来的潜在应用。
