Department of Bioengineering, University of Texas at Dallas, Richardson, TX, 75080, USA.
Enlisense LLC, Allen, TX, USA.
Biosens Bioelectron. 2021 Apr 1;177:112940. doi: 10.1016/j.bios.2020.112940. Epub 2020 Dec 30.
Over the last decade, significant advancements have been made in the field of biosensing technology. With the rising demand for personalized healthcare and health management tools, electrochemical sensors are proving to be reliable solutions; specifically, impedimetric sensors are gaining considerable attention primarily due to their ability to perform label-free sensing. The novel approach of using Room Temperature Ionic Liquids (RTILs) to improve the sensitivity and stability of these detection systems makes long-term continuous sensing feasible towards a wide range of sensing applications, predominantly biosensing. Through this review, we aim to provide an update on current scientific progress in using impedimetric biosensing combined with RTILs for the development of sensitive biosensing platforms. This review also summarizes the latest trends in the field of biosensing and provides an update on the current challenges that remain unsolved.
在过去的十年中，生物传感技术领域取得了重大进展。随着人们对个性化医疗和健康管理工具的需求不断增加，电化学传感器被证明是可靠的解决方案；特别是，由于其能够进行无标记传感，阻抗传感器受到了相当大的关注。使用室温离子液体 (RTILs) 来提高这些检测系统的灵敏度和稳定性的新方法使得长期连续传感成为可能，适用于广泛的传感应用，主要是生物传感。通过本次综述，我们旨在提供使用阻抗生物传感结合 RTILs 开发灵敏生物传感平台的当前科学进展的最新信息。本文还总结了生物传感领域的最新趋势，并介绍了当前仍未解决的挑战。
