PHARes-MéRISP Team, Univ. Bordeaux, ISPED, Inserm, UMR 1219 Bordeaux Population Health, Bordeaux, France
University Bordeaux, Bordeaux, France.
BMJ Open. 2022 Aug 11;12(8):e065361. doi: 10.1136/bmjopen-2022-065361.
Addiction is considered a chronic disease associated with a high rate of relapse as a consequence of the addictive condition. Most of the current therapeutic work focuses on the notion of relapse prevention or avoidance and the control of its determinants. Since only a small portion of patients can access alcohol addiction treatment, it is crucial to find a way to offer new support towards safe consumptions, reductions or cessations. The harm reduction (HR) approach and mental health recovery perspective offers another way to support the patient with alcohol addiction. Vitae is a realist evaluation of the impact, viability and transferability of the IACA! programme, an HR programme based on the principle of psychosocial recovery for people with alcohol use disorders.
The Vitae study adheres to the theory-driven evaluation framework where the realist evaluation method and contribution analysis are used to explore the effects, mechanisms and influence of context on the outcomes and to develop and adjust an intervention theory. This study is a 12-month, multi-case, longitudinal descriptive pilot study using mixed methods. It is multi-centred, and carried out in 10 addiction treatment or prevention centres. In this study, outcomes are related to the evolution of alcohol use and the beneficiaries trajectory in terms of psychosocial recovery during these 12 months after the start of IACA!. The target number of participants are 100 beneficiaries and 23 professionals.
This research was approved by the Committee for the Protection of Persons Ouest V n°: 21/008-3HPS and was reported to the French National Agency for the Safety of Health Products. All participants will provide consent prior to participation. The results will be reported in international peer-reviewed journals and presented at scientific and public conferences.
NCT04927455; ID-RCB2020-A03371-38.
成瘾被认为是一种与高复发率相关的慢性疾病，这是成瘾状态的结果。目前大多数的治疗工作都集中在预防或避免复发的概念上，以及控制其决定因素上。由于只有一小部分患者能够接受酒精成瘾治疗，因此找到一种方法来提供新的支持，以实现安全消费、减少或停止饮酒是至关重要的。减少伤害（HR）方法和心理健康康复视角为支持酒精成瘾患者提供了另一种方式。Vitae 是对 IACA! 计划（一个基于心理社会康复原则的针对酒精使用障碍者的 HR 计划）的影响、可行性和可转移性的真实评估。
Vitae 研究遵循理论驱动的评估框架，其中使用真实评估方法和贡献分析来探索效果、机制和背景对结果的影响，并开发和调整干预理论。这项研究是一项为期 12 个月的多案例、纵向描述性试点研究，采用混合方法。它是多中心的，在 10 个成瘾治疗或预防中心进行。在这项研究中，结果与酒精使用的演变以及在 IACA!开始后 12 个月内心理社会康复方面的受益人的轨迹有关。目标参与者人数为 100 名受益人和 23 名专业人员。
这项研究得到了西部保护人员委员会的批准，编号为：21/008-3HPS，并向法国国家卫生产品安全局报告。所有参与者将在参与之前提供同意。研究结果将在国际同行评议期刊上报告，并在科学和公共会议上展示。
NCT04927455；ID-RCB2020-A03371-38。
