Katamine S, Tanaami S, Sekimoto K, Hoshino N, Totsuka K, Suzuki M
Drugs Exp Clin Res. 1987;13(1):1-4.
The effects of a diet including high-iodine eggs, containing much higher amounts of iodine than ordinary eggs, were investigated on lipid metabolism and thyroid function in rats. To a non-purified diet was added at the 1% (w/w) level ordinary egg power (OE diet: 35 micrograms iodine/100 g diet) or high-iodine egg powder (IE diet: 392 micrograms iodine/100 g diet). At 7 months and 19 months, feeding of the IE diet resulted in a lowered serum triacylglycerol level, elevated tissue lipoprotein lipase activity and a lowered lipid peroxide level in the brain. Although the serum total iodine level was 5 times higher in animals given the IE diet than in those given the OE diet, serum levels of thyroid-related hormones (TSH, T3 and T4) were not affected by feeding of the IE diet. In animals exposed to cold and given antithyroid drug treatment, the IE diet seemed to improve age-related defects in thermogenic and thyroid hormone responses to cold, and also to confer resistance to the antithyroid drug. These results suggest that iodine ingestion through high-iodine eggs modulates both lipid metabolism and thyroid function in rats.
研究了食用含碘量远高于普通鸡蛋的高碘蛋对大鼠脂质代谢和甲状腺功能的影响。在非纯化日粮中按1%（w/w）的比例添加普通鸡蛋粉（OE日粮：35微克碘/100克日粮）或高碘鸡蛋粉（IE日粮：392微克碘/100克日粮）。在7个月和19个月时，喂食IE日粮可降低血清三酰甘油水平，提高组织脂蛋白脂肪酶活性，并降低大脑中的脂质过氧化物水平。虽然喂食IE日粮的动物血清总碘水平比喂食OE日粮的动物高5倍，但IE日粮的喂食并未影响血清甲状腺相关激素（促甲状腺激素、T3和T4）水平。在暴露于寒冷环境并接受抗甲状腺药物治疗的动物中，IE日粮似乎改善了与年龄相关的产热和甲状腺激素对寒冷反应的缺陷，并且还赋予了对抗甲状腺药物的抗性。这些结果表明，通过高碘蛋摄入碘可调节大鼠的脂质代谢和甲状腺功能。
