Katamine S, Hoshino N, Totsuka K, Suzuki M
J Nutr Sci Vitaminol (Tokyo). 1985 Jun;31(3):339-53. doi: 10.3177/jnsv.31.339.
The present paper describes the effects of long-term (17-19 months) feeding of high-iodine eggs on lipid metabolism and thyroid function of rats, and also the effects of inorganic iodine on lipid metabolism. Rats were meal-fed on a diet containing 1% (w/w) of ordinary egg powder (OE diet as control: 35 micrograms I/100 g) or high-iodine egg powder (IE diet: 392 micrograms I/100 g). After the 19-month dietary treatment, rats fed on the IE diet, compared with the controls, showed a higher tissue lipoprotein lipase activity, a lower lipid peroxide level in the brain and a trend toward lower serum triacylglycerol levels and body fat storage without alterations in serum levels of thyroid-related hormones (TSH, T3 and T4). From the results of cold exposure and anti-thyroid drug-treatment conducted on rats fed on the OE and IE diets for 17 months, high-iodine eggs seemed to improve the age-related defects in thermogenic and thyroid hormone responses to cold, and also to result in a resistance to the anti-thyroid drug. The effects of the IE diet on lipid metabolism of rats were partly exhibited by feeding of the OE diet with an equivalent amount of iodine added as KI or KIO3. Thus, it is suggested that iodine ingestion through high-iodine eggs modulates both lipid metabolism and thyroid function in rats.
本文描述了长期（17 - 19个月）喂食高碘蛋对大鼠脂质代谢和甲状腺功能的影响，以及无机碘对脂质代谢的影响。大鼠按餐喂食含1%（w/w）普通蛋粉的日粮（OE日粮作为对照：35微克碘/100克）或高碘蛋粉（IE日粮：392微克碘/100克）。经过19个月的日粮处理后，与对照组相比，喂食IE日粮的大鼠表现出较高的组织脂蛋白脂肪酶活性、较低的脑脂质过氧化物水平以及血清三酰甘油水平和体脂储存有降低的趋势，而血清甲状腺相关激素（促甲状腺激素、T3和T4）水平无变化。根据对喂食OE和IE日粮17个月的大鼠进行冷暴露和抗甲状腺药物处理的结果，高碘蛋似乎改善了与年龄相关的产热和甲状腺激素对寒冷反应的缺陷，并且还导致对抗甲状腺药物产生抗性。通过在OE日粮中添加等量的碘化钾或碘酸钾喂食来部分展现IE日粮对大鼠脂质代谢的影响。因此，提示通过高碘蛋摄入碘可调节大鼠的脂质代谢和甲状腺功能。
