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龙眼果肉(桂圆)多糖的提取、纯化、结构特征及生物活性综述

Extraction, purification, structural features and biological activities of longan fruit pulp (Longyan) polysaccharides: A review.

作者信息

Yue Xuan, Chen Zhejie, Zhang Jinming, Huang Chi, Zhao Shiyi, Li Xuebo, Qu Yan, Zhang Chen

机构信息

State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, China.

出版信息

Front Nutr. 2022 Jul 25;9:914679. doi: 10.3389/fnut.2022.914679. eCollection 2022.

Abstract

. (also called as longan) is a subtropical and tropical evergreen tree belonging to the Sapindaceae family and is widely distributed in China, Southeast Asia and South Asia. The pulp of longan fruit is a time-honored traditional medicinal and edible raw material in China and some Asian countries. With the advancement of food therapy in modern medicine, longan fruit pulp as an edible medicinal material is expected to usher in its rapid development as a functional nutrient. As one of the main constituents of longan fruit pulp, longan fruit pulp polysaccharides (LPs) play an indispensable role in longan fruit pulp-based functional utilization. This review aims to outline the extraction and purification methods, structural characteristics and biological activities (such as immunoregulatory, anti-tumor, prebiotic, anti-oxidant, anti-inflammatory and inhibition of AChE activity) of LPs. Besides, the structure-activity relationship, application prospect and patent application of LPs were analyzed and summarized. Through the systematic summary, this review attempts to provide a theoretical basis for further research of LPs, and promote the industrial development of this class of polysaccharides.

摘要

龙眼(也称为桂圆)是一种属于无患子科的亚热带和热带常绿乔木,广泛分布于中国、东南亚和南亚。龙眼果肉是中国和一些亚洲国家历史悠久的传统药食两用原料。随着现代医学中食疗的发展,龙眼果肉作为一种可食用的药材有望作为功能性营养物质迎来快速发展。作为龙眼果肉的主要成分之一,龙眼果肉多糖(LPs)在基于龙眼果肉的功能性利用中发挥着不可或缺的作用。本综述旨在概述LPs的提取和纯化方法、结构特征和生物活性(如免疫调节、抗肿瘤、益生元、抗氧化、抗炎和抑制乙酰胆碱酯酶活性)。此外,还对LPs的构效关系、应用前景和专利申请进行了分析和总结。通过系统总结,本综述试图为LPs的进一步研究提供理论依据,并推动这类多糖的产业发展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96c1/9358249/09c224736d3c/fnut-09-914679-g0001.jpg

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