Wouters E J, de Jong P A, Cornelissen P J, Kurver P H, van Oel W C, van Woensel C L
Eur J Obstet Gynecol Reprod Biol. 1987 May;25(1):35-41. doi: 10.1016/0028-2243(87)90090-6.
Fetal outcome in 77 uneventful pregnancies was examined and related to venous cord carboxyhaemoglobin (HbCO) levels. 30 women were smokers, 47 were non-smokers. Birth weight and birth weight centiles were found to be substantially reduced in children of mothers who smoked. HbCO levels were significantly elevated in venous cord blood of children of smokers compared with non-smokers. The role of fetal HbCO as a causal factor in reducing birth weight centiles of children of smoking mothers is discussed. It is concluded that carboxyhaemoglobin concentration in fetal venous cord blood did not account for fetal growth retardation in pregnant women who smoked.
对77例正常妊娠的胎儿结局进行了检查，并将其与脐静脉血中碳氧血红蛋白（HbCO）水平相关联。30名女性为吸烟者，47名女性为非吸烟者。结果发现，吸烟母亲的孩子出生体重和出生体重百分位数显著降低。与非吸烟者相比，吸烟者孩子的脐静脉血中HbCO水平显著升高。讨论了胎儿HbCO作为导致吸烟母亲孩子出生体重百分位数降低的因果因素的作用。得出的结论是，胎儿脐静脉血中的碳氧血红蛋白浓度并不能解释吸烟孕妇的胎儿生长受限情况。
