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Single-cell RNA sequencing reveals spatial heterogeneity and immune evasion of circulating tumor cells.

作者信息

Sun Yunfan, Zhou Jian, Fan Jia, Yang Xinrong

机构信息

Department of Liver Surgery & Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai 200032, China.

出版信息

Cancer Biol Med. 2021 Nov 24;18(4):934-6. doi: 10.20892/j.issn.2095-3941.2021.0466.

DOI:10.20892/j.issn.2095-3941.2021.0466
PMID:35959966
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8610158/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8421/8610158/a5bb722b4926/cbm-18-934-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8421/8610158/3d993619a820/cbm-18-934-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8421/8610158/a5bb722b4926/cbm-18-934-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8421/8610158/3d993619a820/cbm-18-934-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8421/8610158/a5bb722b4926/cbm-18-934-g002.jpg

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本文引用的文献

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Clin Cancer Res. 2018 Feb 1;24(3):547-559. doi: 10.1158/1078-0432.CCR-17-1063. Epub 2017 Oct 25.
2
Fluid shear stress activates YAP1 to promote cancer cell motility.流体切应力激活 YAP1 以促进癌细胞迁移。
Nat Commun. 2017 Jan 18;8:14122. doi: 10.1038/ncomms14122.
3
Circulating and disseminated tumour cells - mechanisms of immune surveillance and escape.
通过单细胞 RNA 测序对健康和癌性肝脏中的 NK 细胞进行全景比较。
Cancer Biol Med. 2022 Jul 21;19(9):1334-51. doi: 10.20892/j.issn.2095-3941.2022.0050.
循环肿瘤细胞和播散肿瘤细胞——免疫监视和逃逸的机制。
Nat Rev Clin Oncol. 2017 Mar;14(3):155-167. doi: 10.1038/nrclinonc.2016.144. Epub 2016 Sep 20.
4
Cancer. Circulating tumor cells.癌症。循环肿瘤细胞。
Science. 2013 Sep 13;341(6151):1186-8. doi: 10.1126/science.1235226.
5
Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition.循环肿瘤细胞在上皮和间充质组成上表现出动态变化。
Science. 2013 Feb 1;339(6119):580-4. doi: 10.1126/science.1228522.
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Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer.循环肿瘤细胞中雄激素受体信号作为激素反应性前列腺癌的标志物。
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