Kuroki Shoei, Ayabe Takanori, Tanaka Hiroyuki, Nakada Hiroshi, Maeda Ryo
Department of Thoracic and Breast Surgery, Faculty of Medicine, University of Miyazaki, Kihara 5200, Kiyotake, Miyazaki, 889-1692, Japan.
Department of Pathology, University of Miyazaki, Miyazaki, Japan.
Surg Case Rep. 2022 Aug 12;8(1):154. doi: 10.1186/s40792-022-01510-w.
Spontaneous regression of thymic carcinoma is extremely rare. We report a case of a resected thymic carcinoma with preoperative spontaneous regression in a 67-year-old woman.
The patient presented with low-grade fever and anterior chest pain. Chest computed tomography (CT) showed a 55 × 43 mm exophytic heterogeneously enhancing mass showing some areas of necrosis. Chest CT done one day preoperatively revealed that the tumor had rapidly shrunk for one month. Surgical resection was performed to obtain a definitive diagnosis and achieve complete resection, yielding a postoperative diagnosis of thymic carcinoma. The patient survived without signs of recurrence for 12 months postoperatively.
Mediastinal tumors with necrosis demonstrating spontaneous regression should include thymic carcinomas in the differential diagnosis.
胸腺癌的自发消退极为罕见。我们报告一例67岁女性经手术切除的胸腺癌，术前出现自发消退。
患者表现为低热和前胸疼痛。胸部计算机断层扫描（CT）显示一个55×43毫米的外生性肿块，强化不均匀，有一些坏死区域。术前一天进行的胸部CT显示，肿瘤在一个月内迅速缩小。进行手术切除以获得明确诊断并实现完全切除，术后诊断为胸腺癌。患者术后存活12个月，无复发迹象。
鉴别诊断中，有坏死表现且自发消退的纵隔肿瘤应包括胸腺癌。
