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丙烯酰胺:爆米花中的一种神经毒素——系统评价与荟萃分析

Acrylamide; a neurotoxin in popcorns: a systematic review and meta-analysis.

作者信息

Abedini Amirhossein, Zirak Mohammad-Reza, Akbari Nader, Saatloo Naiema Vakili, Badeenezhad Ahmad, Sadighara Parisa

机构信息

Department of Environmental Health, Food Safety Division, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Rev Environ Health. 2022 Aug 12;38(4):647-653. doi: 10.1515/reveh-2022-0085. Print 2023 Dec 15.

DOI:10.1515/reveh-2022-0085
PMID:35960600
Abstract

Acrylamide is a known neurotoxic compound for humans. Foods that have high concentrations of acrylamide need to be identified. One of the food products containing acrylamide is popcorn. Popcorn is an important source of snacks for children, especially students. The presented study is a systematic review and meta-analysis of the level of acrylamide in popcorn. The search was done in different databases with the keywords; acrylamide, popcorn, popped corn. 27 articles were found by searching various databases. After initial screening and full text evaluation, 8 articles were selected for systematic review and 6 articles for meta-analysis. The amount of acrylamide in this product was in the range of 1,017.7-106 μg/kg. Microwaved corn contains lower amounts of acrylamide than other methods of preparation. The type of popcorn also had an effect on the amount of acrylamide with Meta-regression. It was found that sweet popcorn contains higher amounts of acrylamide. The overall value of acrylamide concentration in popcorns was calculated to be 459.6 ± 220.3 μg/kg. This amount is high and requires measures to reduce the amount of acrylamide.

摘要

丙烯酰胺是一种已知的对人类具有神经毒性的化合物。需要识别出含有高浓度丙烯酰胺的食品。含有丙烯酰胺的食品之一是爆米花。爆米花是儿童尤其是学生零食的重要来源。本研究是对爆米花中丙烯酰胺含量的系统评价和荟萃分析。通过在不同数据库中使用关键词“丙烯酰胺”“爆米花”“爆米”进行检索。通过搜索各种数据库共找到27篇文章。经过初步筛选和全文评估,选择了8篇文章进行系统评价,6篇文章进行荟萃分析。该产品中丙烯酰胺的含量在1017.7 - 106μg/kg范围内。微波爆米花中的丙烯酰胺含量低于其他制备方法。爆米花的类型对丙烯酰胺含量也有影响(通过Meta回归分析)。发现甜爆米花含有较高含量的丙烯酰胺。爆米花中丙烯酰胺浓度的总体值经计算为459.6±220.3μg/kg。这个含量很高,需要采取措施降低丙烯酰胺的含量。

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