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肾移植受者腹侧疝和切口疝修补术的差异

Variation of ventral and incisional hernia repairs in kidney transplant recipients.

作者信息

Solano Quintin P, Thumma Jyothi R, Mullens Cody, Howard Ryan, Ehlers Anne, Delaney Lia, Fry Brian, Shen Mary, Englesbe Michael, Dimick Justin, Telem Dana

机构信息

University of Michigan Medical School, Ann Arbor, MI, USA.

Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA.

出版信息

Surg Endosc. 2023 Apr;37(4):3173-3179. doi: 10.1007/s00464-022-09505-2. Epub 2022 Aug 12.

Abstract

INTRODUCTION

As survivorship following kidney transplant continues to improve, so does the probability of intervening on common surgical conditions, such as ventral or incisional hernia, in this population. Ventral hernia management is known to vary across institutions and this variation has an impact on patient outcomes. We sought to evaluate hospital level variation of ventral or incisional hernia repair (VIHR) in the kidney transplant population.

METHODS

We performed a retrospective review of 100% inpatient Medicare claims to identify patients who underwent kidney transplant between 2007 and 2018. The primary outcome was 1- and 3-year ventral or incisional risk- and reliability-adjusted VIHR rates. Patient and hospital characteristics were evaluated across risk- and reliability-adjusted VIHR rate tertiles. Models were adjusted for age, sex, race, and Elixhauser comorbidities.

RESULTS

Overall, 139,741 patients underwent kidney transplant during the study period with a mean age (SD) of 51.6 (13.7) years. 84,717 (60.6%) were male, and 72,657 (52.0%) were white. Median follow up time was 5.4 years. 2098 (1.50%) patients underwent VIHR. the 1 year risk- and reliability-adjusted hernia repair rates were 0.49% (95% Conf idence Interval (CI) 0.48-0.51, range 0.31-0.59) in tertile 1, 0.63% (95% CI 0.62-0.63, range 0.59-0.68) in tertile 2, and 0.98 (95% CI 0.91-1.05, range 0.68-2.94) in tertile 3. Accordingly, compared to hospitals in tertile 1, the odds of post-transplant hernia repair tertile 2 hospitals were 1.78 (95% CI 1.37-2.31) and at tertile 3 hospitals 3.53 (95% CI 2.87-4.33).

CONCLUSIONS

In a large cohort of Medicare patients undergoing kidney transplant, the overall cumulative incidence of hernia repair varied substantially across hospital tertiles. Patient and hospital characteristics varied across tertile, most notably in diabetes and obesity. Future research is needed to understand if program and surgeon level factors are contributing to the observed variation in treatment of this common disease.

摘要

引言

随着肾移植受者生存率的不断提高,该人群中因常见外科疾病(如腹侧或切口疝)而接受干预的可能性也在增加。众所周知,不同机构对腹侧疝的处理方式存在差异,这种差异会影响患者的治疗效果。我们旨在评估肾移植人群中腹侧或切口疝修补术(VIHR)在医院层面的差异。

方法

我们对100%的住院医疗保险索赔进行了回顾性分析,以确定2007年至2018年间接受肾移植的患者。主要结局指标为1年和3年经风险和可靠性调整后的腹侧或切口疝修补率。根据经风险和可靠性调整后的VIHR率三分位数对患者和医院特征进行评估。模型对年龄、性别、种族和埃利克斯豪泽合并症进行了校正。

结果

总体而言,在研究期间,139,741例患者接受了肾移植,平均年龄(标准差)为51.6(13.7)岁。84,717例(60.6%)为男性,72,657例(52.0%)为白人。中位随访时间为5.4年。2098例(1.50%)患者接受了VIHR。在第一三分位数中,1年经风险和可靠性调整后的疝修补率为0.49%(95%置信区间[CI]0.48 - 0.51,范围0.31 - 0.59),在第二三分位数中为0.63%(95%CI 0.62 - 0.63,范围0.59 - 0.68),在第三三分位数中为0.98(95%CI 0.91 - 1.05,范围0.68 - 2.94)。因此,与第一三分位数的医院相比,第二三分位数医院移植后疝修补的比值比为1.78(95%CI 1.37 - 2.31),第三三分位数医院为3.53(95%CI 2.87 - 4.33)。

结论

在一大群接受肾移植的医疗保险患者中,疝修补的总体累积发生率在医院三分位数间差异很大。患者和医院特征在三分位数间有所不同,最显著的是糖尿病和肥胖情况。需要进一步研究以了解项目和外科医生层面的因素是否导致了这种常见疾病治疗中观察到的差异。

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