Division of Medicine, UCL Centre for Obesity Research, University College London, London, UK.
Bariatric Centre for Weight Management and Metabolic Surgery, University College London Hospital, London, UK.
Intern Emerg Med. 2022 Oct;17(7):2031-2038. doi: 10.1007/s11739-022-03063-0. Epub 2022 Aug 14.
'Hedonic hunger' indicates the desire to consume food in the absence of an energy requirement. Hedonic hunger can be investigated using the validated Power of Food Scale (PFS). Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are currently the most effective treatment options for severe obesity. Following RYGB, hedonic hunger diminishes, which may contribute to sustained weight loss. There are no data examining the effect of SG on hedonic hunger. We prospectively evaluated hedonic hunger using PFS in patients with severe obesity prior to and 6 months after SG (n = 95) or RYGB (n = 44) and investigated the procedure-specific relationship between percentage weight loss (%WL) and hedonic hunger. Anthropometric data were collected at baseline after 6 months, 12 months and 24 months post-operatively. PFS contains 15 items grouped into 3 domains considering when food is: available (FA), present (FP), tasted (FT) and a total score (TS). At 6 months, a significant reduction was seen in all categories post-SG (p < 0.0001) and in TS (p = 0.003), FA (p = 0.0006) and FP (p = 0.0007) post-RYGB. A significantly larger reduction in FP scores was seen post-SG (p = 0.01). Post-SG, a significant correlation with 6-month %WL was noted for changes in FP (p = 0.03) and TS (p = 0.03). Post-SG changes in FP and TS predicted 24-month %WL. Post-RYGB significant correlations were seen between 6-month %WL and dFA (p = 0.04) and dFP (p = 0.03). Changes in FA, FP and TS were predictive of 12-month %WL. HH is reduced following both SG and RYGB with a greater reduction following SG and is related to post-operative %WL. PFS may have a role as a predictive tool for post-operative outcomes following SG and RYGB.
“享乐性饥饿”是指在没有能量需求的情况下渴望进食。可以使用经过验证的食物力量量表(PFS)来研究享乐性饥饿。胃旁路手术(RYGB)和袖状胃切除术(SG)是目前治疗严重肥胖症最有效的治疗方法。RYGB 术后,享乐性饥饿感减弱,这可能有助于持续减肥。目前尚无数据研究 SG 对享乐性饥饿的影响。我们前瞻性地使用 PFS 评估了严重肥胖症患者在 SG(n=95)或 RYGB(n=44)前后的享乐性饥饿,并研究了特定手术与体重减轻百分比(%WL)和享乐性饥饿之间的关系。在手术后 6 个月、12 个月和 24 个月收集了基线时的人体测量数据。PFS 包含 15 个项目,分为 3 个域,考虑食物何时可用(FA)、存在(FP)、品尝(FT)和总分(TS)。SG 术后 6 个月,所有类别均显著降低(p<0.0001),TS(p=0.003)、FA(p=0.0006)和 FP(p=0.0007)也显著降低。SG 术后 FP 评分显著降低(p=0.01)。SG 术后 6 个月,FP 和 TS 的变化与 WL 显著相关(p=0.03)。SG 术后,FP 和 TS 的变化可预测 24 个月的 WL。RYGB 术后,6 个月 WL 与 dFA(p=0.04)和 dFP(p=0.03)显著相关。FA、FP 和 TS 的变化可预测 12 个月的 WL。SG 和 RYGB 术后 HH 均降低,SG 术后降低更明显,与术后 WL 相关。PFS 可能是预测 SG 和 RYGB 术后结果的有用工具。