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近一半的慢性肌腱病患者可能存在神经病理性疼痛成分,不同肌腱部位之间存在显著差异:一项对300多名患者的前瞻性队列研究。

Nearly half of patients with chronic tendinopathy may have a neuropathic pain component, with significant differences seen between different tendon sites: a prospective cohort of more than 300 patients.

作者信息

Wheeler Patrick C

机构信息

Department of Sport and Exercise Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK.

SSEHS, Loughborough University, Loughborough, UK.

出版信息

BMJ Open Sport Exerc Med. 2022 Jul 19;8(3):e001297. doi: 10.1136/bmjsem-2021-001297. eCollection 2022.

Abstract

OBJECTIVES

Identifying the prevalence of neuropathic pain components in patients with chronic tendinopathy conditions using the Self-Administered Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) questionnaire.

METHODS

Patients with chronic tendinopathy and 'tendon-like' conditions treated within a single hospital outpatient clinic specialising in tendinopathy were identified. Pain scores, plus global function patient-reported outcome measures (5-Level version of EuroQol-5 Dimension and Musculoskeletal Health Questionnaire (MSK-HQ)), were completed and compared with the S-LANSS questionnaire.

RESULTS

341 suitable patients with chronic tendinopathy and potentially similar conditions were identified. Numbers: lateral elbow tendinopathy (39), greater trochanteric pain syndrome (GTPS; 112), patellar tendinopathy (11), non-insertional Achilles tendinopathy (40), insertional Achilles tendinopathy (39), plantar fasciopathy (100). 68% were female, with a mean age of 54.0±11.3 years and a mean symptom duration of 38.1±33.7 months.There was a mean S-LANSS score of 11.4±6.4. Overall, 47% of patients scored 12 or greater points on S-LANSS, indicating the possible presence of neuropathic pain. The highest proportion was in patients with plantar fasciopathy (61%), the lowest in those with GTPS (33%). Weak correlations were found between the S-LANSS score and MSK-HQ score, the numerical rating scale (0-10) values for 'average pain' and for 'worst pain', but not with the MSK-HQ %health value.

CONCLUSION

S-LANSS identified nearly half of patients with chronic tendinopathy as possibly having a neuropathic pain component. This is of unclear clinical significance but worth further study to see if/how this may relate to treatment outcomes. These results are from a single hospital clinic dealing with patients with chronic tendinopathy, without a control group or those with shorter symptom duration. However, this reinforces the probability of neuropathic pain components in at least some patients with chronic tendinopathy.

摘要

目的

使用利兹神经病理性症状和体征自评问卷(S-LANSS)确定慢性肌腱病患者中神经病理性疼痛成分的患病率。

方法

确定在一家专门治疗肌腱病的医院门诊接受治疗的慢性肌腱病和“类肌腱”疾病患者。完成疼痛评分以及患者报告的整体功能结局指标(欧洲五维健康量表5级版本和肌肉骨骼健康问卷(MSK-HQ)),并与S-LANSS问卷进行比较。

结果

确定了341例患有慢性肌腱病及可能类似疾病的合适患者。数量如下:外侧肘肌腱病(39例)、大转子疼痛综合征(GTPS;112例)、髌腱肌腱病(11例)、非止点性跟腱肌腱病(40例)、止点性跟腱肌腱病(39例)、足底筋膜炎(100例)。68%为女性,平均年龄54.0±11.3岁 , 平均症状持续时间38.1±33.7个月。S-LANSS平均评分为11.4±6.4。总体而言,47%的患者在S-LANSS上得分12分或更高,表明可能存在神经病理性疼痛。比例最高的是足底筋膜炎患者(61%),最低的是GTPS患者(33%)。发现S-LANSS评分与MSK-HQ评分、“平均疼痛”和“最严重疼痛”的数字评定量表(0-10)值之间存在弱相关性,但与MSK-HQ健康值百分比无关。

结论

S-LANSS确定近一半的慢性肌腱病患者可能存在神经病理性疼痛成分。这一情况的临床意义尚不清楚,但值得进一步研究,以了解这是否以及如何与治疗结果相关。这些结果来自一家治疗慢性肌腱病患者的医院门诊,没有对照组或症状持续时间较短的患者。然而,这进一步证实了至少部分慢性肌腱病患者存在神经病理性疼痛成分的可能性。

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