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马来西亚武吉美拉湖微量元素的生物累积与健康风险评估

Bioaccumulation and Health Risk Assessment of Trace Elements in in Bukit Merah Lake, Malaysia.

作者信息

Abdullah Mohd Ilman Che, Md Shah Amir Shah Ruddin, Haris Hazzeman

机构信息

School of Biological Sciences, Universiti Sains Malaysia, 11800 USM Pulau Pinang, Malaysia.

出版信息

Trop Life Sci Res. 2022 Jul;33(2):179-195. doi: 10.21315/tlsr2022.33.2.9. Epub 2022 Jul 15.

Abstract

This study aims to determine the level of nine trace elements - As, Cd, Cr, Cu, Fe, Mn, Ni, Pb and Zn in liver, gill and muscle of in Bukit Merah Lake (BML). The concentration of trace elements was measured using Inductively Coupled Plasma-Optical Emission Spectrometers (ICP-OES). Cd and Ni were found below the detection level, while Cr was only detected in gill and muscle tissues. The Metal Pollution Index (MPI) established were liver > gill > muscle. The ranking order of trace elements in the gills was Fe > Zn > Mn > Pb > As > Cu > Cr. For the liver, the ranking order was Fe > Cu > Zn > As > Mn > Pb, while in the muscle, the ranking order was Fe > Zn > Pb > As > Cu > Mn > Cr. The estimated daily intake (EDI) for all the trace elements in this study was calculated based on 168 g.day of Malaysians' fish consumption, indicating no potential risk. From the human health point of view, there was no significant non-carcinogenic risk of individual trace elements as evaluated by Target Hazard Quotient (THQ). As indicated by the Hazardous Index (HI), the cumulative effect of all trace elements also suggested no potential of non-carcinogenic risk. The carcinogenic risks assessed from Pb and As were also neglectable and there was no likelihood of getting cancer during one's life span.

摘要

本研究旨在测定武吉美拉湖(BML)中[鱼名未给出]肝脏、鳃和肌肉中9种微量元素——砷、镉、铬、铜、铁、锰、镍、铅和锌的含量水平。使用电感耦合等离子体发射光谱仪(ICP - OES)测定微量元素的浓度。镉和镍低于检测水平,而铬仅在鳃和肌肉组织中被检测到。所建立的金属污染指数(MPI)为肝脏>鳃>肌肉。鳃中微量元素的排序为铁>锌>锰>铅>砷>铜>铬。对于肝脏,排序为铁>铜>锌>砷>锰>铅,而在肌肉中,排序为铁>锌>铅>砷>铜>锰>铬。本研究中所有微量元素的估计每日摄入量(EDI)是根据马来西亚人每天食用168克鱼计算得出的,表明不存在潜在风险。从人体健康角度来看,通过目标危害商数(THQ)评估,单个微量元素不存在显著的非致癌风险。如危害指数(HI)所示,所有微量元素的累积效应也表明不存在非致癌风险的可能性。由铅和砷评估得出的致癌风险也可忽略不计,一生中患癌症的可能性不大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be6d/9354902/c83dfd459232/TLSR-33-2-179-g001.jpg

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