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公共卫生与转化研究的交叉融合。

Cross fertilisation of Public Health and Translational Research.

作者信息

Singaram Muthu, Muraleedhran V R, Sivaprakasam Mohanasankar

机构信息

Healthcare Technology Innovation Centre (HTIC), Indian Institute of Technology Madras (IITM), Chennai, India.

HSS Department and Centre for Technology and Policy, Indian Institute of Technology Madras (IITM), Chennai, India.

出版信息

J Indian Inst Sci. 2022;102(2):763-782. doi: 10.1007/s41745-022-00317-w. Epub 2022 Aug 10.

DOI:10.1007/s41745-022-00317-w
PMID:35968232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9364283/
Abstract

Public health is defined as the science of protecting the safety and improving the health of communities through education, policy-making and research for the prevention of disease (Gatseva and Argirova in J Public Health 19(3):205-6, 2011, 10.1007/s10389-011-0412-8; Winslow in Mod Med 2(1306):183-91, 1920. 10.1126/science.51.1306.23; What is public health. Centers for Disease Control Foundation. Centers for Disease Control, Atlanta, https://www.cdcfoundation.org/what-public-health; What is the WHO definition of health? from the Preamble to the Constitution of WHO as adopted by the International Health Conference, New York, On 7 April 1948. The definition has not been amended since. 22 July 1946; signed by the representatives of 61 States (Official Records of WHO, no. 2, p. 100) and entered into force, 19 June;1948. https://web.archive.org/web/20190307113324/https:/www.who.int/about/who-we-are/frequently-asked-questions). Translational research in healthcare is not only useful and satisfying for the researchers to bring their work to market but it would also support public health by bringing affordable, attainable and scalable solutions to the community at large. This is of high significance because instead of increasing the GDP spent in public health, we should focus on the increasing the translational research spending, as this would lead to improved solutions. Hence, the public health offering would reach a larger community at an improved cost. The COVID-19 pandemic and the huge number of lives it claimed exposes challenges in the public health. The pandemic has caused economic and social disruption to millions of people around the world, with many falling into extreme poverty. In early 2021, it was estimated nearly 690 million people are undernourished and by end of 2021 to increase further by 132 million (Joint statement by ILO, FAO, IFAD and WHO. Impact of COVID-19 on people's livelihoods, their health and our food systems https://www.who.int/news/item/13-10-2020-impact-of-covid-19-on-people's-livelihoods-their-health-and-our-food-systems). The spending for public health has increased many folds during the pandemic and this is where translational research in healthcare can play a transformative role to reduce the burden on government healthcare budget (Covid-19 and its impact on Indian society. https://timesofindia.indiatimes.com/readersblog/covid-19-and-its-impact-on-india/covid-19-and-its-impact-on-indian-society-27565/). Over the past decade, public health research has started playing a major role in Indian academic settings. COVID-19 pandemic has further highlighted the role of public health. However, the potential of using technological advancement has not been fully utilised. This is where translational research and public health can play a role to tap the full potential of technology. This review paper explores the public health practices to understand the different practices to examine how both public health and translational research can cross-fertilise. It concludes with a short discussion on implications on policymakers.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/281f/9364283/5af335a71936/41745_2022_317_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/281f/9364283/012965d6b428/41745_2022_317_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/281f/9364283/2b709766fda0/41745_2022_317_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/281f/9364283/88b7f376bd74/41745_2022_317_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/281f/9364283/45a0ef45b851/41745_2022_317_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/281f/9364283/2389ed896200/41745_2022_317_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/281f/9364283/5af335a71936/41745_2022_317_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/281f/9364283/012965d6b428/41745_2022_317_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/281f/9364283/2b709766fda0/41745_2022_317_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/281f/9364283/88b7f376bd74/41745_2022_317_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/281f/9364283/45a0ef45b851/41745_2022_317_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/281f/9364283/2389ed896200/41745_2022_317_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/281f/9364283/5af335a71936/41745_2022_317_Fig6_HTML.jpg
摘要

公共卫生被定义为通过教育、政策制定和疾病预防研究来保护社区安全并改善其健康状况的科学(加采娃和阿尔吉罗娃,《公共卫生杂志》,第19卷第3期,第205 - 206页,2011年,doi:10.1007/s10389 - 011 - 0412 - 8;温斯洛,《现代医学》,第2卷第1306期,第183 - 191页,1920年,doi:10.1126/science.51.1306.23;什么是公共卫生。疾病控制基金会。疾病控制中心,亚特兰大,https://www.cdcfoundation.org/what - public - health;世界卫生组织对健康的定义是什么?源自1948年4月7日纽约国际卫生会议通过的《世界卫生组织组织法》序言。自1946年7月22日以来该定义未作修订;由61个国家的代表签署(《世界卫生组织正式记录》,第2号,第100页)并于1948年6月19日生效。https://web.archive.org/web/20190307113324/https:/www.who.int/about/who - we - are/frequently - asked - questions)。医疗保健领域的转化研究不仅对研究人员将其工作推向市场很有用且令人满足,还能通过为广大社区带来负担得起、可获得且可扩展的解决方案来支持公共卫生。这具有重要意义,因为我们不应专注于增加公共卫生方面的国内生产总值支出,而应将重点放在增加转化研究支出上,因为这将带来更好的解决方案。因此,公共卫生服务将以更低的成本惠及更多社区。新冠疫情及其造成的大量人员死亡暴露出公共卫生领域存在的挑战。这场疫情给全球数百万人带来了经济和社会混乱,许多人陷入极端贫困。2021年初,据估计近6.9亿人营养不良,到2021年底这一数字将进一步增加1.32亿(国际劳工组织、联合国粮食及农业组织、国际农业发展基金和世界卫生组织联合声明。新冠疫情对人们生计、健康和我们粮食系统的影响https://www.who.int/news/item/13 - 10 - 2020 - impact - of - covid - 19 - on - people's - livelihoods - their - health - and - our - food - systems)。疫情期间公共卫生支出增加了许多倍,而这正是医疗保健领域的转化研究能够发挥变革性作用以减轻政府医疗预算负担的地方(新冠疫情及其对印度社会的影响。https://timesofindia.indiatimes.com/readersblog/covid - 19 - and - its - impact - on - india/covid - 19 - and - its - impact - on - indian - society - 27565/)。在过去十年中,公共卫生研究在印度学术环境中开始发挥重要作用。新冠疫情进一步凸显了公共卫生所起的作用。然而,技术进步的潜力尚未得到充分利用。这正是转化研究和公共卫生能够发挥作用以挖掘技术全部潜力的地方。这篇综述文章探讨了公共卫生实践,以了解不同的实践方式,审视公共卫生和转化研究如何相互促进。文章最后简要讨论了对政策制定者的影响。

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