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[代谢综合征与癌症风险]

[Metabolic syndrome and cancer risk].

作者信息

Scherübl Hans

出版信息

Dtsch Med Wochenschr. 2022 Aug;147(16):1068-1077. doi: 10.1055/a-1868-9164. Epub 2022 Aug 15.

Abstract

Cancer has become a leading cause of death among patients with metabolic syndrome (MetS). The more components of MetS a patient has, the higher his risk of cancer. MetS is causally associated with colorectal, pancreatic, gallbladder, biliary, hepatocellular, gastric, esophageal, thyroid, breast, endometrial and renal cell cancers. MetS increases cancer mortality up to 2,4-fold. Intentional long-term weight loss reduces the excess cancer risk of obese MetS-patients. Both a low-risk lifestyle and cancer screening are effective and decrease the burden of cancer.

摘要

癌症已成为代谢综合征(MetS)患者的主要死因。患者患有的MetS组成部分越多,患癌风险就越高。MetS与结直肠癌、胰腺癌、胆囊癌、胆管癌、肝细胞癌、胃癌、食管癌、甲状腺癌、乳腺癌、子宫内膜癌和肾细胞癌存在因果关联。MetS可使癌症死亡率增加高达2.4倍。有意识的长期体重减轻可降低肥胖MetS患者的额外癌症风险。低风险生活方式和癌症筛查均有效,并可减轻癌症负担。

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