美国 2 个慢性乙型肝炎患者队列中乙型肝炎病毒 delta 检测性能不佳。
Low Performance of Hepatitis Delta Virus Testing Among 2 National Cohorts of Chronic Hepatitis B Patients in the United States.
机构信息
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Palo Alto, California, USA.
Gastroenterology Section Veterans Affairs Palo Alto Healthcare System, Palo Alto, California, USA.
出版信息
Am J Gastroenterol. 2022 Dec 1;117(12):2067-2070. doi: 10.14309/ajg.0000000000001947. Epub 2022 Aug 12.
INTRODUCTION
The purpose of this study was to evaluate hepatitis delta virus (HDV) testing patterns among US adults with chronic hepatitis B (CHB).
METHODS
HDV testing was evaluated among CHB patients using Quest Diagnostics (2016-2020) and Veterans Affairs (2010-2020) data.
RESULTS
Among 157,333 CHB patients (Quest), 6.7% received HDV testing, among which 2.2% were positive. HDV testing was higher in male patients, younger individuals, and patients with advanced liver disease. Among 12,002 CHB patients (Veterans Affairs), 19.7% received HDV testing, among which 3.1% were positive. HDV testing was higher in younger individuals and Asians.
DISCUSSION
Low HDV testing was observed among 2 large US cohorts of adults with CHB.
简介
本研究旨在评估美国慢性乙型肝炎（CHB）成人中乙型肝炎 delta 病毒（HDV）检测模式。
方法
使用 Quest Diagnostics（2016-2020 年）和 Veterans Affairs（2010-2020 年）的数据评估 CHB 患者的 HDV 检测情况。
结果
在 157333 名 CHB 患者（Quest）中，6.7%接受了 HDV 检测，其中 2.2%为阳性。男性患者、年龄较小的患者和患有晚期肝病的患者 HDV 检测率较高。在 12002 名 CHB 患者（退伍军人事务部）中，19.7%接受了 HDV 检测，其中 3.1%为阳性。年龄较小的患者和亚洲人 HDV 检测率较高。
讨论
在 2 个大型美国 CHB 成人队列中，HDV 检测率较低。
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