Green H J, Hughson R L, Thomson J A, Sharratt M T
J Appl Physiol (1985). 1987 May;62(5):1944-53. doi: 10.1152/jappl.1987.62.5.1944.
The effect of an exercise-induced reduction in blood O2-carrying capacity on ventilatory gas exchange and acid-base balance during supramaximal exercise was studied in six males [peak O2 consumption (VO2peak), 3.98 +/- 0.49 l/min]. Three consecutive days of supramaximal exercise resulted in a preexercise reduction of hemoglobin concentration from 15.8 to 14.0 g/dl (P less than 0.05). During exercise (120% VO2peak) performed intermittently (1 min work to 4 min rest); a small but significant (P less than 0.05) increase was found for both O2 consumption (VO2) (l X min) and heart rate (beats/min) on day 2 of the training. On day 3, VO2 (l/min) was reduced 3.2% (P less than 0.05) over day 1 values. No changes were found in CO2 output and minute ventilation during exercise between training days. Similarly, short-term training failed to significantly alter the changes in arterialized blood PCO2, pH, and [HCO-3] observed during exercise. It is concluded that hypervolemia-induced reductions in O2-carrying capacity in the order of 10-11% cause minimal impairment to gas exchange and acid-base balance during supramaximal non-steady-state exercise.
研究了六名男性[最大摄氧量（VO₂peak）为3.98±0.49升/分钟]在力竭运动期间，运动诱导的血液携氧能力降低对通气气体交换和酸碱平衡的影响。连续三天进行力竭运动导致运动前血红蛋白浓度从15.8克/分升降至14.0克/分升（P<0.05）。在间歇进行的运动（1分钟运动，4分钟休息）（运动强度为120%VO₂peak）过程中，训练第2天的耗氧量（VO₂）（升/分钟）和心率（次/分钟）均出现了小幅度但显著的（P<0.05）升高。在第3天，VO₂（升/分钟）较第1天的值降低了3.2%（P<0.05）。训练期间各天运动过程中的二氧化碳排出量和分钟通气量均未发生变化。同样，短期训练未能显著改变运动期间观察到的动脉化血液PCO₂、pH值和[HCO₃⁻]的变化。研究得出结论，血容量过多导致的携氧能力降低约10 - 11%，在力竭非稳态运动期间对气体交换和酸碱平衡造成的损害最小。
