Green H J, Thomson J A, Houston M E
J Appl Physiol (1985). 1987 May;62(5):1954-61. doi: 10.1152/jappl.1987.62.5.1954.
Blood and muscle substrates and metabolites were investigated in six healthy males (ranging in age from 19 to 23 yr) during three consecutive days of supramaximal exercise training. Muscle biopsies from the vastus lateralis and arterialized blood samples from a hand vein were extracted before the exercise and at selected times during the intermittent (1 min work to 4 min rest) cycling. The results indicated that blood glucose concentration was significantly depressed (P less than 0.05) on both days 2 and 3 of the training, whereas plasma free fatty acids and blood glycerol, pyruvate, alanine, and lactate were unaffected. At the muscle level, glucose and lactate concentrations were depressed on days 2 and 3, whereas ATP and glycogen were reduced only on the final day of training. No training-induced alterations were noted for muscle glucose 6-phosphate or muscle ADP. These results indicate that the approximate 10-11% reduction in O2-carrying capacity accompanying the short-term training does not directly and negatively influence muscle energy metabolism during the exercise. Rather, the explanation for the altered muscle and blood constituents must be sought from other effects of the training such as impaired carbohydrate repletion.
在连续三天进行超最大运动训练期间，对六名健康男性（年龄在19至23岁之间）的血液和肌肉底物及代谢物进行了研究。在运动前以及间歇性（1分钟工作至4分钟休息）骑行期间的选定时间，采集了股外侧肌的肌肉活检样本和手部静脉的动脉化血样。结果表明，训练的第2天和第3天，血糖浓度显著降低（P<0.05），而血浆游离脂肪酸、血液甘油、丙酮酸、丙氨酸和乳酸未受影响。在肌肉水平上，第2天和第3天葡萄糖和乳酸浓度降低，而ATP和糖原仅在训练的最后一天减少。未观察到训练引起的肌肉6-磷酸葡萄糖或肌肉ADP的改变。这些结果表明，短期训练伴随的约10-11%的携氧能力降低不会直接对运动期间的肌肉能量代谢产生负面影响。相反，肌肉和血液成分改变的解释必须从训练的其他影响因素中寻找，如碳水化合物补充受损。
