• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Novel insights into the role of anti-inflammatory IL-38 in immunity against infection.抗炎性白细胞介素-38在抗感染免疫中作用的新见解
Cell Mol Immunol. 2022 Nov;19(11):1322-1324. doi: 10.1038/s41423-022-00876-z. Epub 2022 Aug 16.
2
Anti-inflammatory cytokines directly inhibit innate but not adaptive CD8+ T cell functions.抗炎细胞因子直接抑制先天性而非适应性CD8 + T细胞功能。
J Virol. 2014 Jul;88(13):7474-84. doi: 10.1128/JVI.00658-14. Epub 2014 Apr 16.
3
CD8 T cells in innate immune responses: using STAT4-dependent but antigen-independent pathways to gamma interferon during viral infection.天然免疫应答中的CD8 T细胞：在病毒感染期间利用依赖STAT4但不依赖抗原的途径产生γ干扰素。
mBio. 2014 Oct 21;5(5):e01978-14. doi: 10.1128/mBio.01978-14.
4
Cytokines in innate and acquired immunity to Trypanosoma cruzi infection.先天性和获得性免疫应对克氏锥虫感染中的细胞因子
Braz J Med Biol Res. 1998 Jan;31(1):117-21. doi: 10.1590/s0100-879x1998000100015.
5
Interleukin-4 weakens host resistance to pulmonary and disseminated cryptococcal infection caused by combined treatment with interferon-gamma-inducing cytokines.白细胞介素-4会削弱宿主对由诱导γ-干扰素的细胞因子联合治疗所引发的肺部和播散性隐球菌感染的抵抗力。
Cell Immunol. 1999 Oct 10;197(1):55-61. doi: 10.1006/cimm.1999.1557.
6
Type 1 Innate Lymphoid Cell and Natural Killer Cells Are Sources of Interferon-γ and Other Inflammatory Cytokines Associated With Distinct Clinical Presentation in Early Dengue Infection.1 型固有淋巴细胞和自然杀伤细胞是与登革热早期感染的不同临床表现相关的干扰素-γ和其他炎症细胞因子的来源。
J Infect Dis. 2022 Jan 5;225(1):84-93. doi: 10.1093/infdis/jiab312.
7
The Roles of Type I Interferon in Bacterial Infection.I型干扰素在细菌感染中的作用。
Cell Host Microbe. 2016 Jun 8;19(6):760-9. doi: 10.1016/j.chom.2016.05.016.
8
Innate immunity components and cytokines in gastric mucosa in children with Helicobacter pylori infection.幽门螺杆菌感染儿童胃黏膜中的固有免疫成分及细胞因子
Mediators Inflamm. 2015;2015:176726. doi: 10.1155/2015/176726. Epub 2015 Apr 8.
9
Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway.干扰素调节因子 3 通过激活 PI3K/Akt 通路在小胶质细胞中发挥抗炎作用。
J Neuroinflammation. 2011 Dec 30;8:187. doi: 10.1186/1742-2094-8-187.
10
Delineation of the innate and adaptive T-cell immune outcome in the human host in response to Campylobacter jejuni infection.阐明人类宿主对空肠弯曲菌感染的固有和适应性 T 细胞免疫应答结果。
PLoS One. 2010 Nov 9;5(11):e15398. doi: 10.1371/journal.pone.0015398.

引用本文的文献

1
Sepsis-induced immunosuppression: mechanisms, biomarkers and immunotherapy.脓毒症诱导的免疫抑制：机制、生物标志物与免疫治疗。
Front Immunol. 2025 Apr 29;16:1577105. doi: 10.3389/fimmu.2025.1577105. eCollection 2025.
2
Nanoplastics: Immune Impact, Detection, and Internalization after Human Blood Exposure by Single-Cell Mass Cytometry.纳米塑料：人体血液暴露后通过单细胞质谱流式细胞术检测其免疫影响及内化情况
Adv Mater. 2025 Mar;37(12):e2413413. doi: 10.1002/adma.202413413. Epub 2024 Oct 24.
3
The 5' untranslated region variant rs3811050 C/T of the interleukin-38 encoding gene is associated with susceptibility to rheumatoid arthritis in Iraqi women.白细胞介素-38 编码基因的 5'非翻译区变异 rs3811050 C/T 与伊拉克女性类风湿关节炎易感性相关。
Mol Biol Rep. 2024 Apr 29;51(1):589. doi: 10.1007/s11033-024-09529-y.
4
Characterization of METRNβ as a novel biomarker of Coronavirus disease 2019 severity and prognosis.METRNβ 作为新型生物标志物用于评估 2019 年冠状病毒病严重程度和预后。
Front Immunol. 2023 Jan 31;14:1111920. doi: 10.3389/fimmu.2023.1111920. eCollection 2023.

本文引用的文献

1
Evaluation of interleukin-38 levels in serum of patients with coronavirus disease 2019.评估 2019 冠状病毒病患者血清中白细胞介素-38 水平。
J Med Virol. 2022 Aug;94(8):3642-3652. doi: 10.1002/jmv.27762. Epub 2022 Apr 14.
2
An overview of the biological and multifunctional roles of IL-38 in different infectious diseases and COVID-19.IL-38 在不同传染病和 COVID-19 中的生物学和多功能作用概述。
Immunol Res. 2022 Jun;70(3):316-324. doi: 10.1007/s12026-022-09275-y. Epub 2022 Mar 8.
3
IL-38 Alleviates Inflammation in Sepsis in Mice by Inhibiting Macrophage Apoptosis and Activation of the NLRP3 Inflammasome.IL-38 通过抑制巨噬细胞凋亡和激活 NLRP3 炎性体减轻小鼠脓毒症中的炎症。
Mediators Inflamm. 2021 Dec 17;2021:6370911. doi: 10.1155/2021/6370911. eCollection 2021.
4
IL-38 prevents induction of trained immunity by inhibition of mTOR signaling.IL-38 通过抑制 mTOR 信号来阻止训练免疫的诱导。
J Leukoc Biol. 2021 Nov;110(5):907-915. doi: 10.1002/JLB.3A0220-143RRR. Epub 2021 Feb 23.
5
Interleukin-38 ameliorates poly(I:C) induced lung inflammation: therapeutic implications in respiratory viral infections.白细胞介素-38 可改善聚肌苷酸-聚胞苷酸诱导的肺部炎症：在呼吸道病毒感染中的治疗意义。
Cell Death Dis. 2021 Jan 7;12(1):53. doi: 10.1038/s41419-020-03283-2.
6
Interleukin-38 protects against sepsis by augmenting immunosuppressive activity of CD4 CD25 regulatory T cells.白细胞介素-38 通过增强 CD4 CD25 调节性 T 细胞的免疫抑制活性来预防败血症。
J Cell Mol Med. 2020 Jan;24(2):2027-2039. doi: 10.1111/jcmm.14902. Epub 2019 Dec 27.
7
IL-38 is a biomarker for acute respiratory distress syndrome in humans and down-regulates Th17 differentiation in vivo.白细胞介素-38是人类急性呼吸窘迫综合征的一种生物标志物，并且在体内下调辅助性T细胞17（Th17）的分化。
Clin Immunol. 2020 Jan;210:108315. doi: 10.1016/j.clim.2019.108315. Epub 2019 Nov 20.
8
Anti-inflammatory mechanisms of the novel cytokine interleukin-38 in allergic asthma.新型细胞因子白细胞介素-38在过敏性哮喘中的抗炎机制
Cell Mol Immunol. 2020 Jun;17(6):631-646. doi: 10.1038/s41423-019-0300-7. Epub 2019 Oct 23.
9
Interleukin 38 Protects Against Lethal Sepsis.白细胞介素 38 可预防致死性败血症。
J Infect Dis. 2018 Aug 24;218(7):1175-1184. doi: 10.1093/infdis/jiy289.
10
Elevated serum interleukin-38 level at baseline predicts virological response in telbivudine-treated patients with chronic hepatitis B.基线时血清白细胞介素-38水平升高可预测替比夫定治疗的慢性乙型肝炎患者的病毒学应答。
World J Gastroenterol. 2016 May 14;22(18):4529-37. doi: 10.3748/wjg.v22.i18.4529.

Novel insights into the role of anti-inflammatory IL-38 in immunity against infection.

作者信息

Gao Xun, Wu Guoqiu, Tsang Miranda Sin-Man, Huang Danqi, Lam Christopher Wai-Kei, Wong Chun Kwok

机构信息

Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong, China.

Center of Clinical Laboratory Medicine, Zhongda Hospital, Southeast University, Nanjing, China.

出版信息

Cell Mol Immunol. 2022 Nov;19(11):1322-1324. doi: 10.1038/s41423-022-00876-z. Epub 2022 Aug 16.

DOI:10.1038/s41423-022-00876-z
PMID:35974108
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9379218/
Abstract
摘要