Davies J P, O'Connor D O, Greer J A, Harris W H
J Biomed Mater Res. 1987 Jun;21(6):719-30. doi: 10.1002/jbm.820210604.
The mechanical properties of the three cement preparations most widely used in the United States were compared by conducting tensile and fatigue tests on Simplex P, LVC, and Zimmer Regular bone cements. Specimens of all three cement preparations were prepared for mechanical testing with and without centrifugation of the cement immediately after mixing. Although the results of the tensile testing revealed a few specific instances of significant differences in the tensile properties of the three cement preparations, there was no consistent evidence that one cement was superior in tension to the others. However, the fatigue properties of Simplex P were consistently and significantly superior to the fatigue properties of both LVC and Zimmer Regular bone cements. Centrifugation of the cement immediately after mixing significantly improved both the tensile and fatigue properties of all three bone cements. However, the fatigue strength of centrifuged Simplex P was substantially and significantly superior to the fatigue strength of the centrifuged LVC and Zimmer Regular bone cements. Since in total joint replacements bone cement is subjected to cyclic loading, these data suggest that centrifuged Simplex P is a preferable bone cement to LVC and to Zimmer Regular cement with or without centrifugation.
通过对Simplex P、LVC和Zimmer常规骨水泥进行拉伸和疲劳试验,比较了美国最广泛使用的三种骨水泥制剂的力学性能。在混合后立即对所有三种骨水泥制剂的样本进行离心或不离心处理,以准备进行力学测试。尽管拉伸试验结果显示,在三种骨水泥制剂的拉伸性能方面存在一些显著差异的具体情况,但没有一致的证据表明一种骨水泥在拉伸方面优于其他骨水泥。然而,Simplex P的疲劳性能始终且显著优于LVC和Zimmer常规骨水泥的疲劳性能。混合后立即对骨水泥进行离心处理,显著改善了所有三种骨水泥的拉伸和疲劳性能。然而,离心后的Simplex P的疲劳强度大大且显著优于离心后的LVC和Zimmer常规骨水泥的疲劳强度。由于在全关节置换中骨水泥承受循环载荷,这些数据表明,无论是否进行离心处理,离心后的Simplex P都是比LVC和Zimmer常规骨水泥更优的骨水泥。