McDonald D J, Sim F H
J Bone Joint Surg Am. 1987 Jun;69(5):766-72.
In eighty patients who were seen with Paget's disease of the hip between 1969 and 1982, symptomatic coxarthrosis led to total hip arthroplasty in ninety-one hips. The long-term clinical and radiographic results were analyzed by use of the Mayo Clinic hip-scoring system. The cases of the forty-six patients (fifty-two hips) who had been operated on before 1975 were analyzed ten years after the arthroplasty. In this group, the incidence of aseptic loosening that required revision was approximately 15 per cent; radiographic evidence of loosening was evident in approximately 30 per cent of the femoral components and approximately 14 per cent of the acetabular components. Actuarial analysis comparing these forty-six patients with our over-all experience of total hip arthroplasty during the same period of time in 7,222 hips of patients who did not have Paget's disease revealed an increase of slight statistical significance in the incidence of revision for aseptic loosening in the patients who had Paget's disease. However, the over-all result was good or excellent in 74 per cent of these patients, suggesting that replacement of the hip using cemented components remains an acceptable form of treatment for degenerative coxarthrosis secondary to Paget's disease.
1969年至1982年间，对80例患有髋关节佩吉特病的患者进行了观察，其中91例髋关节因症状性髋关节炎接受了全髋关节置换术。采用梅奥诊所髋关节评分系统对长期临床和影像学结果进行分析。对1975年前接受手术的46例患者（52髋）的病例在关节置换术后10年进行分析。在该组中，需要翻修的无菌性松动发生率约为15%；约30%的股骨假体和14%的髋臼假体有影像学松动证据。将这46例患者与同期我们对7222例无佩吉特病患者进行全髋关节置换术的总体经验进行精算分析，结果显示佩吉特病患者无菌性松动翻修发生率有轻微统计学意义的增加。然而，这些患者中74%的总体结果为良好或优秀，这表明使用骨水泥型假体进行髋关节置换仍是治疗佩吉特病继发的退行性髋关节炎的一种可接受的治疗方式。
