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微生物之旅:从珠穆朗玛峰到火星

Microbial Journey: Mount Everest to Mars.

作者信息

Sood Utkarsh, Dhingra Gauri Garg, Anand Shailly, Hira Princy, Kumar Roshan, Kaur Jasvinder, Verma Mansi, Singhvi Nirjara, Lal Sukanya, Rawat Charu Dogra, Singh Vineet Kumar, Kaur Jaspreet, Verma Helianthous, Tripathi Charu, Singh Priya, Dua Ankita, Saxena Anjali, Phartyal Rajendra, Jayaraj Perumal, Makhija Seema, Gupta Renu, Sahni Sumit, Nayyar Namita, Abraham Jeeva Susan, Somasundaram Sripoorna, Lata Pushp, Solanki Renu, Mahato Nitish Kumar, Prakash Om, Bala Kiran, Kumari Rashmi, Toteja Ravi, Kalia Vipin Chandra, Lal Rup

机构信息

The Energy and Resources Institute, New Delhi, India.

Kirori Mal College, University of Delhi, Delhi, India.

出版信息

Indian J Microbiol. 2022 Sep;62(3):323-337. doi: 10.1007/s12088-022-01029-6. Epub 2022 Jul 2.

Abstract

A rigorous exploration of microbial diversity has revealed its presence on Earth, deep oceans, and vast space. The presence of microbial life in diverse environmental conditions, ranging from moderate to extreme temperature, pH, salinity, oxygen, radiations, and altitudes, has provided the necessary impetus to search for them by extending the limits of their habitats. Microbiology started as a distinct science in the mid-nineteenth century and has provided inputs for the betterment of mankind during the last 150 years. As beneficial microbes are assets and pathogens are detrimental, studying both have its own merits. Scientists are nowadays working on illustrating the microbial dynamics in Earth's subsurface, deep sea, and polar regions. In addition to studying the role of microbes in the environment, the microbe-host interactions in humans, animals and plants are also unearthing newer insights that can help us to improve the health of the host by modulating the microbiota. Microbes have the potential to remediate persistent organic pollutants. Antimicrobial resistance which is a serious concern can also be tackled only after monitoring the spread of resistant microbes using disciplines of genomics and metagenomics The cognizance of microbiology has reached the top of the world. Space Missions are now looking for signs of life on the planets (specifically Mars), the Moon and beyond them. Among the most potent pieces of evidence to support the existence of life is to look for microbial, plant, and animal fossils. There is also an urgent need to deliberate and communicate these findings to layman and policymakers that would help them to take an adequate decision for better health and the environment around us. Here, we present a glimpse of recent advancements by scientists from around the world, exploring and exploiting microbial diversity.

摘要

对微生物多样性的深入探索揭示了其在地球、深海和广袤太空中的存在。微生物生命存在于从温和到极端的温度、酸碱度、盐度、氧气、辐射和海拔等各种环境条件下,这为通过扩展其栖息地范围来寻找它们提供了必要的动力。微生物学在19世纪中叶成为一门独立的科学,并在过去150年里为人类的福祉提供了助力。由于有益微生物是资产而病原体是有害的,对两者的研究都有其自身的价值。如今,科学家们致力于阐明地球地下、深海和极地地区的微生物动态。除了研究微生物在环境中的作用外,微生物与人类、动物和植物宿主之间的相互作用也在揭示新的见解,这些见解有助于我们通过调节微生物群来改善宿主的健康。微生物有潜力修复持久性有机污染物。只有在利用基因组学和宏基因组学学科监测耐药微生物的传播之后,才能解决作为一个严重问题的抗菌耐药性。微生物学的认知已经达到了世界之巅。太空任务现在正在寻找行星(特别是火星)、月球及其他天体上的生命迹象。支持生命存在的最有力证据之一是寻找微生物、植物和动物化石。还迫切需要向普通民众和政策制定者阐述和交流这些发现,这将有助于他们做出适当的决策,以促进我们周围的健康和环境。在此,我们简要介绍世界各地科学家在探索和利用微生物多样性方面的最新进展。

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