探索蓝藻藻胆蛋白的结构方面和治疗前景。
Exploring the structural aspects and therapeutic perspectives of cyanobacterial phycobiliproteins.
作者信息
Patel Stuti N, Sonani Ravi R, Roy Diya, Singh Niraj Kumar, Subudhi Sanjukta, Pabbi Sunil, Madamwar Datta
机构信息
P. D. Patel Institute of Applied Sciences, Charotar University of Science and Technology, CHARUSAT Campus, Changa, Anand, Gujarat 388421 India.
Post-Graduate Department of Biosciences, UGC-Centre of Advanced Study, Sardar Patel University, Satellite Campus, Vadtal Road, Bakrol, Anand, Gujarat 388315 India.
出版信息
3 Biotech. 2022 Sep;12(9):224. doi: 10.1007/s13205-022-03284-2. Epub 2022 Aug 13.
Phycobiliproteins (PBPs) of cyanobacteria and algae possess unique light harvesting capacity which expand the photosynthetically active region (PAR) and allow them to thrive in extreme niches where higher plants cannot. PBPs of cyanobacteria/algae vary in abundance, types, amino acid composition and in structure as a function of species and the habitat that they grow in. In the present review, the key aspects of structure, stability, and spectral properties of PBPs, and their correlation with ecological niche of cyanobacteria are discussed. Besides their role in light-harvesting, PBPs possess antioxidant, anti-aging, neuroprotective, hepatoprotective and anti-inflammatory properties, which can be used in therapeutics. Recent developments in therapeutic applications of PBPs are reviewed with special focus on '' and ''.
蓝细菌和藻类的藻胆蛋白（PBPs）具有独特的光捕获能力，可扩展光合有效辐射区域（PAR），使它们能够在高等植物无法生存的极端生态位中茁壮成长。蓝细菌/藻类的PBPs在丰度、类型、氨基酸组成和结构上因物种及其生长的栖息地而异。在本综述中，讨论了PBPs的结构、稳定性和光谱特性的关键方面，以及它们与蓝细菌生态位的相关性。除了在光捕获中的作用外，PBPs还具有抗氧化、抗衰老、神经保护、肝脏保护和抗炎特性，可用于治疗。本文综述了PBPs治疗应用的最新进展，特别关注“”和“”。
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