Becker Marte A J, Does de Willebois Eline M L van der, Bemelman Willem A, Wildenberg Manon E, Buskens Christianne J
Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology & Metabolism, Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Department of Surgery, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
Clin Colon Rectal Surg. 2022 Jul 4;35(4):316-320. doi: 10.1055/s-0042-1743589. eCollection 2022 Jul.
Despite the longstanding awareness of the presence of mesenteric alterations in Crohn's disease, the functional and clinical consequences of these alterations remain a topic of debate. Guidelines advise a limited resection without resection of the adjacent mesentery to prevent short bowel syndrome and postoperative complications. However, recently mesenteric resection has been proposed as an alternative to reduce recurrence rates in Crohn's disease patients. Here, we evaluate the data available on this topic in terminal ileitis, both from a fundamental research point of view and clinical perspective.
尽管人们早就认识到克罗恩病存在肠系膜改变，但其功能和临床后果仍是一个有争议的话题。指南建议进行有限切除，不切除相邻的肠系膜，以预防短肠综合征和术后并发症。然而，最近有人提出肠系膜切除作为降低克罗恩病患者复发率的一种替代方法。在此，我们从基础研究和临床角度评估关于终末回肠炎这一主题的现有数据。
