Oral Biology and Biochemistry Research Group, Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal.
Oral Biology and Biochemistry Research Group - LIB-Phys FCT UID/FIS/04559/2013, Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal.
Clin Oral Investig. 2022 Dec;26(12):7167-7177. doi: 10.1007/s00784-022-04678-5. Epub 2022 Aug 17.
To evaluate bleaching efficacy and oral health-related quality of life (ORHQoL) of three bleaching systems with similar hydrogen peroxide (HP) concentration for up to 6 months post-treatment.
A randomized controlled trial was designed with three parallel groups: group A - in-office 6% HP paint-on varnish; group B - at-home 6% HP with adaptable tray; group C - at-home 16% carbamide peroxide with custom tray. At three different stages (baseline, after bleaching, and 6-month follow-up), ORHQoL was evaluated by the OHIP-14 questionnaire and tooth color of the upper canines and central incisors were measured by two shade guides and a spectrophotometer (measuring CIE Lab* with respective color/whiteness differences - ΔE/ΔWI). Results were presented as mean and 95% confidence intervals and statistical tests were performed appropriately, considering a significance level of α = 0.05.
All groups presented significant color differences (P < 0.05) between all stages, with ΔE/ΔWI surpassing the perceptibility threshold in 98% cases, with group C's results being significantly (P < 0.05) higher when compared to other groups, although with significantly (P < 0.05) higher values of color relapse. Significative ORHQoL improvements (P < 0.05) were detected after bleaching in a global analysis with no differences between techniques.
All techniques presented bleaching efficacy, color stability, and improvements in ORHQoL up to 6 months post-treatment.
Clinicians may consider both at-home and in-office bleaching techniques with 6% HP to attain long-lasting satisfactory clinical results while producing positive changes in ORHQoL.
评估 3 种过氧化氢(HP)浓度相似的漂白系统的漂白效果和口腔健康相关生活质量(ORHQoL),随访时间最长达 6 个月。
设计了一项随机对照试验,分为 3 个平行组:A 组 - 诊室 6%HP 涂漆光固化树脂;B 组 - 家庭使用 6%HP 可塑托盘;C 组 - 家庭使用 16%HP 脲素过氧化物定制托盘。在 3 个不同阶段(基线、漂白后和 6 个月随访),通过 OHIP-14 问卷评估 ORHQoL,通过 2 种比色板和分光光度计测量上颌尖牙和中切牙的牙齿颜色(用相应的颜色/白化差异测量 CIE Lab* - ΔE/ΔWI)。结果以均值和 95%置信区间表示,并根据需要进行适当的统计检验,置信水平为α=0.05。
所有组在所有阶段均呈现出显著的颜色差异(P<0.05),ΔE/ΔWI 在 98%的情况下超过了可察觉阈值,C 组的结果与其他组相比显著更高(P<0.05),尽管颜色复发的数值显著更高(P<0.05)。在全球分析中,漂白后 ORHQoL 显著改善(P<0.05),但不同技术之间没有差异。
所有技术在治疗后 6 个月内均显示出漂白效果、颜色稳定性和 ORHQoL 的改善。
临床医生可以考虑使用 6%HP 的诊室和家庭漂白技术,以获得持久的满意临床效果,同时在 ORHQoL 方面产生积极的变化。