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自组装的、具有层次结构的表面在（超）疏水性抗病毒涂层中的应用。

Self-Assembled, Hierarchical Structured Surfaces for Applications in (Super)hydrophobic Antiviral Coatings.

机构信息

Northumbria University, Newcastle upon Tyne NE1 8ST, U.K.

Institute for Multiscale Thermofluids (IMT), School of Engineering, University of Edinburgh, Mayfield Road, Edinburgh EH9 3JL, Scotland, U.K.

出版信息

Langmuir. 2022 Aug 30;38(34):10632-10641. doi: 10.1021/acs.langmuir.2c01579. Epub 2022 Aug 17.

DOI:10.1021/acs.langmuir.2c01579
PMID:35977085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9434993/
Abstract

A versatile method for the creation of multitier hierarchical structured surfaces is reported, which optimizes both antiviral and hydrophobic (easy-clean) properties. The methodology exploits the availability of surface-active chemical groups while also manipulating both the surface micro- and nanostructure to control the way the surface coating interacts with virus particles within a liquid droplet. This methodology has significant advantages over single-tier structured surfaces, including the ability to overcome the droplet-pinning effect and in delivering surfaces with high static contact angles (>130°) and good antiviral efficacy (log kill >2). In addition, the methodology highlights a valuable approach for the creation of mechanically robust, nanostructured surfaces which can be prepared by spray application using nonspecialized equipment.

摘要

本文报道了一种通用的方法，用于构建多层次分层结构表面，该方法同时优化了抗病毒和疏水性（易清洁）性能。该方法利用了表面活性化学基团的可用性，同时还可以操纵表面的微观和纳米结构，以控制表面涂层与液滴内病毒颗粒相互作用的方式。与单层结构表面相比，该方法具有显著的优势，包括克服液滴固定效应的能力，并提供具有高静态接触角（>130°）和良好抗病毒效果（对数杀灭率>2）的表面。此外，该方法还突出了一种有价值的方法，用于创建机械强度高的纳米结构表面，这些表面可以使用非专用设备通过喷涂来制备。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/5993cd2cc395/la2c01579_0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/c0b0ed299954/la2c01579_0001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/9e756aa667d6/la2c01579_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/853da2ca735b/la2c01579_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/d36c282e732e/la2c01579_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/25f9ac1ab105/la2c01579_0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/7814cdba6be8/la2c01579_0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/b2b17dbbc964/la2c01579_0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/322b9f6d3b58/la2c01579_0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/5993cd2cc395/la2c01579_0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/c0b0ed299954/la2c01579_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/5f9c8df03a5e/la2c01579_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/9e756aa667d6/la2c01579_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/853da2ca735b/la2c01579_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/d36c282e732e/la2c01579_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/25f9ac1ab105/la2c01579_0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/7814cdba6be8/la2c01579_0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/b2b17dbbc964/la2c01579_0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/322b9f6d3b58/la2c01579_0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a532/9434993/5993cd2cc395/la2c01579_0010.jpg

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