皮肤利什曼病（东方疖）的临床诊断。

Clinical diagnosis of cutaneous leishmaniasis (oriental sore).

作者信息

Kubba R, Al-Gindan Y, el-Hassan A M, Omer A H

出版信息

J Am Acad Dermatol. 1987 Jun;16(6):1183-9. doi: 10.1016/s0190-9622(87)70155-8.

Abstract

Cutaneous leishmaniasis (oriental sore) is characterized by slowly evolving inflammatory lesion(s) that are nodular, noduloulcerative, or ulcerative and that heal spontaneously with scar(s) in 3 to 12 months. In the course of a comprehensive study of cutaneous leishmaniasis due to Leishmania major in an endemic focus in Saudi Arabia, seven clinical features of diagnostic value were identified and their approximate frequency in a selected group of 475 patients was determined. These features were: exposed site location, 84%; pairing or clustering of lesions, 61.72%; skin crease orientation, 35.37%; volcanic nodules, 30.32%; satellite papules, 19.37%; subcutaneous nodules, 11.37%; and "iceberg" nodules, 4.63%. This information should serve the process of clinical diagnosis and may be relied upon when the procedures for parasite detection are negative or unavailable.

摘要

皮肤利什曼病（东方疖）的特征是炎症性病变发展缓慢，表现为结节状、结节溃疡性或溃疡性，3至12个月后可自发愈合并留下疤痕。在对沙特阿拉伯一个地方性疫源地中由硕大利什曼原虫引起的皮肤利什曼病进行的一项综合研究过程中，确定了七个具有诊断价值的临床特征，并确定了它们在一组475名选定患者中的大致出现频率。这些特征是：暴露部位，84%；病变成对或成簇，61.72%；皮肤褶皱方向，35.37%；火山样结节，30.32%；卫星丘疹，19.37%；皮下结节，11.37%；以及“冰山”结节，4.63%。这些信息应有助于临床诊断过程，并且在寄生虫检测程序为阴性或无法进行时可以作为依据。