Mitoquinone mesylate attenuates brain inflammation in humanized mouse model of chronic HIV infection.
作者信息
Satta Sandro, Hugo Cristelle, Sharma Madhav, Rezek Valerie, Kossyvakis Athanassios, Roy Shubhendu Sen, Kitchen Scott, Kelesidis Theodoros
机构信息
Division of Infectious Diseases.
Division of Hematology and Oncology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
出版信息
AIDS. 2022 Sep 1;36(11):1609-1611. doi: 10.1097/QAD.0000000000003291.
Abstract
摘要
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A novel role of NLRP3-generated IL-1β in the acute-chronic transition of peripheral lipopolysaccharide-elicited neuroinflammation: implications for sepsis-associated neurodegeneration.NLRP3 产生的 IL-1β 在周围脂多糖诱发的神经炎症的急慢性转化中的新作用：对脓毒症相关神经退行性变的影响。
J Neuroinflammation. 2020 Feb 18;17(1):64. doi: 10.1186/s12974-020-1728-5.
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Redox Biol. 2016 Dec;10:200-205. doi: 10.1016/j.redox.2016.10.017. Epub 2016 Oct 27.
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