Lee Jun Sung, Kim Hee Jun, Lee Jin Seok, Yun Hyeok Jun, Lee Suji, Cheong Jae-Ho, Kim Soo Young, Kim Seok-Mo, Chang Hojin, Lee Yong Sang, Park Cheong Soo, Chang Hang-Seok
Department of Surgery, Thyroid Cancer Center, Gangnam Severance Hospital, Institute of Refractory Thyroid Cancer, Yonsei University College of Medicine, Seoul, South Korea.
Department of Surgery, CHA Ilsan Medical Center, Cha University School of Medicine, Goyang-si, South Korea.
Front Surg. 2022 Aug 2;9:940391. doi: 10.3389/fsurg.2022.940391. eCollection 2022.
With the recent advances in thyroid cancer surgery techniques and the increasing number of patients concerned about cosmetics, the use of transoral endoscopic thyroidectomy is increasing globally. The aim of this study was to determine whether transoral endoscopic thyroidectomy is truly a clean-contaminated surgery.
From September 2016 to April 2018, 20 patients with thyroid cancer underwent transoral endoscopic thyroidectomy performed by a single surgeon at Gangnam Severance Hospital. Before and after surgery, the oral cavity was swabbed to obtain culture samples, and antibiotics were administered before and after surgery each once.
Of the total 20 patients, no bacteria were identified before or after surgery in eight (40%) patients. Bacteria were identified both before and after surgery in seven patients (35%). In four patients (20%), bacteria were not identified before surgery, but bacteria were identified after surgery. Bacteria were identified before surgery but not after surgery in one patient (5%). No surgical site infection was observed. All the bacteria identified were normal flora of the oral cavity and skin.
There was no difference between the preoperative culture and postoperative culture of the oral cavity in patients undergoing TOET, and there were no postoperative surgical site infection with prophylactic pre & post-operative antibiotics use. Considering the patient's position and surgical extent in TOET, it appears to be difficult for non-indigenous bacteria to invade the surgical site in oral cavity.
随着甲状腺癌手术技术的最新进展以及越来越多的患者关注美观问题,经口内镜甲状腺切除术在全球范围内的应用正在增加。本研究的目的是确定经口内镜甲状腺切除术是否真的是清洁-污染手术。
2016年9月至2018年4月,20例甲状腺癌患者在江南severance医院由一名外科医生进行了经口内镜甲状腺切除术。手术前后,对口腔进行擦拭以获取培养样本,并且在手术前后各给予一次抗生素。
在总共20例患者中,8例(40%)患者手术前后均未鉴定出细菌。7例患者(35%)手术前后均鉴定出细菌。4例患者(20%)术前未鉴定出细菌,但术后鉴定出细菌。1例患者(5%)术前鉴定出细菌但术后未鉴定出细菌。未观察到手术部位感染。所有鉴定出的细菌均为口腔和皮肤的正常菌群。
接受经口内镜甲状腺切除术的患者口腔术前培养和术后培养之间没有差异,并且在预防性使用术前和术后抗生素的情况下没有术后手术部位感染。考虑到经口内镜甲状腺切除术中患者的体位和手术范围,非本土细菌似乎难以侵入口腔手术部位。