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冷大气等离子体:通过氧化还原稳态治疗癌症?

Cold atmospheric plasma: redox homeostasis to treat cancers?

作者信息

Dai Xiaofeng, Shen Li, Zhang Jianying

机构信息

State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou University, Zhengzhou 450000, China; Wuxi School of Medicine, Jiangnan University, Wuxi 214122, China.

Wuxi School of Medicine, Jiangnan University, Wuxi 214122, China.

出版信息

Trends Biotechnol. 2023 Jan;41(1):15-18. doi: 10.1016/j.tibtech.2022.07.007. Epub 2022 Aug 16.

DOI:10.1016/j.tibtech.2022.07.007
PMID:35985891
Abstract

Cold atmospheric plasma (CAP) is a promising therapeutic for highly aggressive malignancies given its unique safety and selectivity against redox imbalance and is characterized as a tumor microenvironment (TME) sensitizer, immunogenic cell death (ICD) inducer, and cancer stem cell (CSC) killer that functions through the regulation of cell redox homeostasis.

摘要

冷大气等离子体(CAP)是一种很有前景的针对高度侵袭性恶性肿瘤的治疗方法,因为它对氧化还原失衡具有独特的安全性和选择性,其特点是作为一种肿瘤微环境(TME)敏化剂、免疫原性细胞死亡(ICD)诱导剂和癌症干细胞(CSC)杀手,通过调节细胞氧化还原稳态发挥作用。

相似文献

1
Cold atmospheric plasma: redox homeostasis to treat cancers?冷大气等离子体:通过氧化还原稳态治疗癌症?
Trends Biotechnol. 2023 Jan;41(1):15-18. doi: 10.1016/j.tibtech.2022.07.007. Epub 2022 Aug 16.
2
Trident cold atmospheric plasma blocks three cancer survival pathways to overcome therapy resistance.三叉戟冷大气等离子体阻断三种癌症生存途径以克服治疗抗性。
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Cold atmospheric plasma: Novel opportunities for tumor microenvironment targeting.冷等离体子体:靶向肿瘤微环境的新机遇。
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Receptor-Mediated Redox Imbalance: An Emerging Clinical Avenue against Aggressive Cancers.受体介导的氧化还原失衡:对抗侵袭性癌症的新兴临床途径。
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Intracellular Responses Triggered by Cold Atmospheric Plasma and Plasma-Activated Media in Cancer Cells.冷等离体子体和等离子体激活介质在癌细胞中引发的细胞内反应。
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Cold atmospheric plasma, a novel promising anti-cancer treatment modality.冷大气等离子体,一种新型且有前景的抗癌治疗方式。
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Small. 2024 Jun;20(25):e2310018. doi: 10.1002/smll.202310018. Epub 2024 Jan 25.

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Nanomedicine-Driven Modulation of Reductive Stress for Cancer Therapy.纳米医学驱动的还原应激调节用于癌症治疗
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Cancer metastasis: molecular mechanisms and therapeutic interventions.
癌症转移:分子机制与治疗干预
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Unleashing the Power of Cold Atmospheric Plasma: Inducing Mitochondria Damage-Mediated Mitotic Catastrophe.释放冷大气等离子体的力量:诱导线粒体损伤介导的有丝分裂灾难
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Reactive oxygen species from non-thermal gas plasma (CAP): implication for targeting cancer stem cells.非热气体等离子体(冷大气压等离子体)产生的活性氧:对靶向癌症干细胞的意义
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A Two-Stage Transferred Cold Atmospheric Plasma as a Unique Therapeutic Strategy for Targeting Colon Cancer Stem Cells.两阶段转移冷大气等离子体作为靶向结肠癌干细胞的独特治疗策略。
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