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冷大气等离子体:通过氧化还原稳态治疗癌症?

Cold atmospheric plasma: redox homeostasis to treat cancers?

作者信息

Dai Xiaofeng, Shen Li, Zhang Jianying

机构信息

State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou University, Zhengzhou 450000, China; Wuxi School of Medicine, Jiangnan University, Wuxi 214122, China.

Wuxi School of Medicine, Jiangnan University, Wuxi 214122, China.

出版信息

Trends Biotechnol. 2023 Jan;41(1):15-18. doi: 10.1016/j.tibtech.2022.07.007. Epub 2022 Aug 16.

Abstract

Cold atmospheric plasma (CAP) is a promising therapeutic for highly aggressive malignancies given its unique safety and selectivity against redox imbalance and is characterized as a tumor microenvironment (TME) sensitizer, immunogenic cell death (ICD) inducer, and cancer stem cell (CSC) killer that functions through the regulation of cell redox homeostasis.

摘要

冷大气等离子体(CAP)是一种很有前景的针对高度侵袭性恶性肿瘤的治疗方法,因为它对氧化还原失衡具有独特的安全性和选择性,其特点是作为一种肿瘤微环境(TME)敏化剂、免疫原性细胞死亡(ICD)诱导剂和癌症干细胞(CSC)杀手,通过调节细胞氧化还原稳态发挥作用。

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