Han Ding, Zhang Ziyu, Du Bei, Liu Lin, He Meinan, Liu Zhuzhu, Wei Ruihua
Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin 300384, China.
Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin 300384, China.
Cont Lens Anterior Eye. 2023 Feb;46(1):101748. doi: 10.1016/j.clae.2022.101748. Epub 2022 Aug 19.
This study aimed to compare the vision-related quality of life (VRQoL) between Defocus Incorporated Soft Contact (DISC) lenses and single-vision spectacles in Chinese children, in order to evaluate their visual performance and subjective acceptance of this bifocal designed contact lenses treatment.
Chinese participants aged 7 to 12 years, with myopia of -4.00 to -0.75 D, astigmatism < 1.50 D, and monocular best-corrected visual acuity 0.0 or better, were recruited in the study. All participants had been wearing DISC lenses, or single-vision spectacles, for the last 6 to 18 months and were requested to complete the routine ocular examination and Chinese version of the Pediatric Refractive Error Profile (PREP 2) questionnaire. The questionnaire consisted of 7 scales: vision, symptoms, appearance, activities, handling, peer perception, and overall score. According to their habitual correction modalities, fifty-four children were allocated to the DISC group and 56 to the single-vision spectacles group. A generalized linear model was fitted to assess variables associated with the PREP 2 score.
Participants wearing DISC lenses scored significantly higher than those wearing single-vision spectacles for vision, appearance, activities, peer perception, and overall (all P < 0.05). The improvement of VRQoL in the DISC group was mainly represented in appearance, peer perception, and activities. The quality of life improved more for older participants on scales of vision, symptoms, handling, appearance, and overall score (all P < 0.05). The interaction between treatment and age was statistically significant for the activities scale (P < 0.05).
DISC lens wear significantly improves VRQoL in Chinese children compared with single-vision spectacles for most of the survey scales, especially in the areas of appearance, peer perception, and activities. The benefits provided by DISC lenses contribute to greater satisfaction than single-vision spectacles for myopic children.
本研究旨在比较中国儿童使用离焦软镜（DISC）与单焦点眼镜的视力相关生活质量（VRQoL），以评估他们的视觉表现以及对这种双焦点设计隐形眼镜治疗的主观接受度。
招募年龄在7至12岁、近视度数为-4.00至-0.75 D、散光<1.50 D且单眼最佳矫正视力为0.0或更好的中国参与者。所有参与者在过去6至18个月内一直佩戴DISC镜片或单焦点眼镜，并被要求完成常规眼科检查和中文版的儿童屈光不正概况问卷（PREP 2）。该问卷由7个量表组成：视力、症状、外观、活动、佩戴、同伴认知和总分。根据他们习惯的矫正方式，54名儿童被分配到DISC组，56名儿童被分配到单焦点眼镜组。采用广义线性模型来评估与PREP 2评分相关的变量。
佩戴DISC镜片的参与者在视力、外观、活动、同伴认知和总分方面的得分显著高于佩戴单焦点眼镜的参与者（所有P<0.05）。DISC组VRQoL的改善主要体现在外观、同伴认知和活动方面。年龄较大的参与者在视力、症状、佩戴、外观和总分量表上的生活质量改善更大（所有P<0.05）。治疗与年龄之间的交互作用在活动量表上具有统计学意义（P<0.05）。
与单焦点眼镜相比，佩戴DISC镜片在大多数调查量表上显著提高了中国儿童的VRQoL，尤其是在外观、同伴认知和活动方面。DISC镜片带来的益处使近视儿童比佩戴单焦点眼镜更满意。
