Liu Kenneth Ka King, Zhang Han Yu, Leung Daisy Ka Yan, Lam Carly Siu Yin
School of Optometry, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China.
Centre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China.
Front Neurosci. 2024 Dec 3;18:1460062. doi: 10.3389/fnins.2024.1460062. eCollection 2024.
This study evaluates differences in the visual field performance when wearing the Defocus Incorporated Multiple Segments (DIMS) spectacle lens compared to wearing a conventional single vision (SV) spectacle lens.
Twenty-one children aged 9-14 years with spherical equivalent refraction (SER) between -1.13D to -4.75D were recruited. Mid-peripheral near visual acuity (NVA) under room lighting condition (500 lux ±10%) was measured using DIMS and SV lenses, respectively. Automated static perimetry (Zeiss, Humphrey Visual Field HFA 750i) with SITA Fast 30-2 protocol was used to investigate the visual field sensitivity. During the test, the study lens (Plano DIMS or SV lens) were inserted into the lens holder in front of the trial lenses with each child's compensated prescription.
Three children were not able to complete the reliable visual tests due to fixation losses (>20%) or high false positive rate (>15%) while 18 children successfully completed the test. The mean visual field sensitivity was 29.2 ± 3.7 decibels (dB) and 29.3 ± 3.5 dB when wearing DIMS and SV lens, respectively. The mean sensitivity differences between DIMS and SV lens among 76 locations ranged from -2.4 ± 3.9 dB to 1.6 ± 3.9 dB. No statistically significant difference in sensitivity was observed across 76 locations within the central 30 between DIMS and SV lens (Wilcoxon signed rank test with bonferroni correction for multiple comparisons, > 0.00065). Compared to SV lens, 0.05 logarithm of minimal angle of resolution (logMAR) reduction in mid-peripheral NVA in all 4 quadrants (Superior, Temporal, Inferior and nasal, < 0.05) was noted with the DIMS lens ( = 18). However, no statistically significant correlation was found between the mid-peripheral NVA and visual sensitivity at the specific locations.
Although the mid-peripheral NVA was slightly reduced using DIMS lens, wearing DIMS lens did not change the children's visual sensitivity to detect the static stimulus within 30 visual field when compared to wearing SV lens.
本研究评估佩戴离焦整合多焦点（DIMS）眼镜片与佩戴传统单焦点（SV）眼镜片时视野表现的差异。
招募了21名年龄在9至14岁、等效球镜度（SER）在-1.13D至-4.75D之间的儿童。分别使用DIMS镜片和SV镜片在室内照明条件（500勒克斯±10%）下测量中周边近视力（NVA）。采用SITA Fast 30-2程序的自动静态视野计（蔡司，汉弗莱视野分析仪HFA 750i）来研究视野敏感度。在测试过程中，将研究镜片（平光DIMS或SV镜片）插入带有每个孩子矫正处方的测试镜片前的镜片架中。
3名儿童因注视丢失（>20%）或高假阳性率（>15%）未能完成可靠的视力测试，而18名儿童成功完成了测试。佩戴DIMS镜片和SV镜片时，平均视野敏感度分别为29.2±3.7分贝（dB）和29.3±3.5dB。DIMS镜片和SV镜片在76个位置的平均敏感度差异范围为-2.4±3.9dB至1.6±3.9dB。在中央30°范围内的76个位置，DIMS镜片和SV镜片之间未观察到敏感度有统计学显著差异（采用Bonferroni校正进行多次比较的Wilcoxon符号秩检验，P>0.00065）。与SV镜片相比，使用DIMS镜片时在所有4个象限（上、颞、下和鼻侧，P<0.05）的中周边NVA最小分辨角对数（logMAR）降低了0.05（n=18）。然而，在特定位置的中周边NVA与视野敏感度之间未发现统计学显著相关性。
尽管使用DIMS镜片时中周边NVA略有降低，但与佩戴SV镜片相比，佩戴DIMS镜片并未改变儿童在30°视野范围内检测静态刺激的视野敏感度。
