International Center for Island Studies, Kagoshima University.
School of Health Sciences, Faculty of Medicine, Kagoshima University.
J Atheroscler Thromb. 2023 May 1;30(5):481-490. doi: 10.5551/jat.63557. Epub 2022 Aug 20.
In this study, we aim to analyze the correlation between brachial-ankle pulse wave velocity (baPWV) and Suita score or Framingham risk score and obtain the cutoff value of baPWV by sex and age for cardiovascular risk, as assessed by these scores in the large Japanese annual health checkup data.
In total, 25,602 participants (14,539 men and 11,063 women), who had their annual health checkups, were included in this study. Cutoff values of baPWV for the moderate- and high-risk groups stratified by sex and age were obtained using a receiver operating characteristic (ROC) curve analysis.
As per our findings, the Suita score demonstrated better correlations with baPWV than the Framingham risk score in both sexes (men, Suita score R=0.41 and Framingham risk score R=0.37; women, Suita score R=0.54 and Framingham risk score R=0.33). The ROC curve analysis demonstrated the cutoff values of baPWV for moderate- and high-risk groups estimated using the Suita score, and they are as follows: in men, the baPWV cutoff values were 1,350 cm/s in the 40s, 1,430 cm/s in the 50s, 1,520 cm/s in the 60s, and 1,880 cm/s in the 70s. In women, the baPWV cutoff values were 1,350 cm/s in the 40s, 1,430 cm/s in the 50s, 1,570 cm/s in the 60s, and 1,800 cm/s in the 70s.
We demonstrated that baPWV significantly correlated with the Suita score or Framingham risk score in both men and women, with the former presenting a stronger correlation than the latter. We propose the cutoff values of baPWV for moderate- and high-risk groups estimated using the Suita score.
本研究旨在分析臂踝脉搏波速度（baPWV）与 Suita 评分或 Framingham 风险评分的相关性，并根据这些评分在大型日本年度健康检查数据中评估心血管风险，得出男女不同年龄的 baPWV 截断值。
共纳入 25602 名（男性 14539 名，女性 11063 名）接受年度健康检查的参与者。使用受试者工作特征（ROC）曲线分析获得男女按年龄分层的中危和高危组的 baPWV 截断值。
研究结果显示，Suita 评分与男女 baPWV 的相关性均优于 Framingham 风险评分（男性，Suita 评分 R=0.41 和 Framingham 风险评分 R=0.37；女性，Suita 评分 R=0.54 和 Framingham 风险评分 R=0.33）。ROC 曲线分析显示，使用 Suita 评分估算的中危和高危组的 baPWV 截断值如下：男性 40 岁组为 1350cm/s，50 岁组为 1430cm/s，60 岁组为 1520cm/s，70 岁组为 1880cm/s。女性 40 岁组为 1350cm/s，50 岁组为 1430cm/s，60 岁组为 1570cm/s，70 岁组为 1800cm/s。
我们证实，baPWV 与男性和女性的 Suita 评分或 Framingham 风险评分均显著相关，前者的相关性强于后者。我们提出使用 Suita 评分估算的中危和高危组的 baPWV 截断值。
