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希腊的骨与关节结核:一项2011年至2019年的回顾性研究。

Bone and Joint Tuberculosis in Greece: A Retrospective Study From 2011 to 2019.

作者信息

Karabella Irena, Chronopoulos Efstathios, Panagiotakopoulos George, Dontas Ismene A

机构信息

Infectious Diseases, Sotiria Thoracic Diseases Hospital of Athens, Athens, GRC.

Laboratory for Research of the Musculoskeletal System, KAT General Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, GRC.

出版信息

Cureus. 2022 Jul 19;14(7):e27033. doi: 10.7759/cureus.27033. eCollection 2022 Jul.

Abstract

PURPOSE

Bone and joint tuberculosis (BJTB) represents approximately 2-5% of all tuberculosis (TB) cases and its characteristics are infrequently discussed. The aim of this study was to examine the epidemiology, characteristics, and management of BJTB in Greece.

METHODS

We conducted retrospective analyses of demographic clinical and treatment data accessed from medical records of patients with BJTB and with pulmonary involvement between 2011 and 2019 from the national TB reference hospital in Greece. Factors associated with treatment outcomes among patients were evaluated.

RESULTS

Out of the total 3064 confirmed TB cases during the study period, 54 patients had either BJTB or skeletal TB with pulmonary involvement. The majority of patients were males (81.5%) and the mean age of the patients was 37.81±18.92 years. Out of the total patients, 11 were Greek and 43 were immigrants. Women had a higher probability of experiencing a stable or negative treatment outcome. Also, the patients that received therapy for less than nine months had 16.3 times higher probability of experiencing a stable or negative treatment outcome, compared to those that received therapy for more than 12 months.

CONCLUSIONS

The study indicated that the sex and the duration of treatment correlated with the treatment outcomes. It is essential to monitor and accurately report treatment outcomes so as to achieve disease control.

摘要

目的

骨与关节结核(BJTB)约占所有结核病(TB)病例的2 - 5%,但其特征鲜少被讨论。本研究旨在调查希腊BJTB的流行病学、特征及治疗情况。

方法

我们对2011年至2019年期间从希腊国家结核病参考医院获取的BJTB及合并肺部受累患者的病历中的人口统计学、临床和治疗数据进行了回顾性分析。评估了与患者治疗结果相关的因素。

结果

在研究期间确诊的3064例结核病病例中,54例患有BJTB或合并肺部受累的骨结核。大多数患者为男性(81.5%),患者的平均年龄为37.81±18.92岁。在所有患者中,11例为希腊人,43例为移民。女性获得稳定或阴性治疗结果的可能性更高。此外,接受治疗少于9个月的患者获得稳定或阴性治疗结果的可能性是接受治疗超过12个月患者的16.3倍。

结论

该研究表明性别和治疗持续时间与治疗结果相关。监测并准确报告治疗结果对于实现疾病控制至关重要。

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本文引用的文献

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Retrospective Study of Bone-TB in Oman: 2002-2019.阿曼骨结核的回顾性研究:2002-2019 年。
J Epidemiol Glob Health. 2021 Jun;11(2):238-245. doi: 10.2991/jegh.k.210420.002. Epub 2021 Apr 26.
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Tuberculosis: a timeless challenge for medicine.结核病:医学永恒的挑战。
J Prev Med Hyg. 2020 Jul 4;61(2):E143-E147. doi: 10.15167/2421-4248/jpmh2020.61.2.1402. eCollection 2020 Jun.
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