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老年患者肩关节镜手术中瑞芬太尼联合右美托咪定静脉麻醉复合臂丛神经阻滞的回顾性分析

Retrospective analysis of remifentanil combined with dexmedetomidine intravenous anesthesia combined with brachial plexus block on shoulder arthroscopic surgery in elderly patients.

作者信息

Zhang Yan, Zhao Lingling, Lv Liangce, Li Songxue

机构信息

Yan Zhang, Department of Anesthesiology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 800 Huangjiahuayuan Road,Shanghai 201803, P.R. China.

Lingling Zhao, Department of Anesthesiology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 800 Huangjiahuayuan Road,Shanghai 201803, P.R. China.

出版信息

Pak J Med Sci. 2022 Jul-Aug;38(6):1546-1551. doi: 10.12669/pjms.38.6.5724.

Abstract

OBJECTIVES

To analyze the effect of remifentanil combined with dexmedetomidine intravenous anesthesia combined with brachial plexus block on shoulder arthroscopic surgery in elderly patients.

METHODS

This retrospective study conducted at Jiading Branch of Shanghai General Hospital, investigated clinical data from elderly patients receiving shoulder arthroscopy between January 2020 and June 2021. Based on the treatment, patients were retrospectively divided into Group-I (remifentanil combined with dexmedetomidine) and Group-II (remifentanil continuous pump injection). Hemodynamic indices, such as mean arterial pressure (MAP) and heart rate (HR), degree of pain (VAS score), and stress response marker levels were examined prior to the operation and at various time points post-operation. Operation time and adverse reaction incidences were also evaluated.

RESULTS

There was no significant differences in MAP and HR between the two groups prior to the operation. However, MAP and HR levels were lower in Group-I patients at three time points post-operation. Similarly, VAS scores were not different between the two groups prior to the operation but were much lower in Group-I at multiple time points post-operation. The same trend was observed for the stress-induced angiotensin-II, cortisol, and aldosterone. Additionally, patients in Group-I had lower incidence of adverse reactions and shorter operation time.

CONCLUSION

Remifentanil combined with dexmedetomidine intravenous anesthesia for shoulder arthroscopic surgery under general anesthesia combined with brachial plexus block in elderly patients can maintain hemodynamic stability, shorten operation time, reduce the degree of stress reaction, pain caused by invasive operation, and reduce the incidence of adverse reactions.

摘要

目的

分析瑞芬太尼联合右美托咪定静脉麻醉联合臂丛神经阻滞对老年患者肩关节镜手术的影响。

方法

本回顾性研究在上海交通大学医学院附属瑞金医院北院进行,调查了2020年1月至2021年6月期间接受肩关节镜检查的老年患者的临床资料。根据治疗方法,将患者回顾性分为第一组(瑞芬太尼联合右美托咪定)和第二组(瑞芬太尼持续泵注)。在手术前和术后各个时间点检查血流动力学指标,如平均动脉压(MAP)和心率(HR)、疼痛程度(VAS评分)以及应激反应标志物水平。还评估了手术时间和不良反应发生率。

结果

两组患者术前MAP和HR无显著差异。然而,第一组患者术后三个时间点的MAP和HR水平较低。同样,两组患者术前VAS评分无差异,但第一组患者术后多个时间点的VAS评分要低得多。应激诱导的血管紧张素II、皮质醇和醛固酮也观察到相同趋势。此外,第一组患者的不良反应发生率较低,手术时间较短。

结论

在老年患者全身麻醉联合臂丛神经阻滞下,瑞芬太尼联合右美托咪定静脉麻醉用于肩关节镜手术可维持血流动力学稳定,缩短手术时间,减轻应激反应程度、侵入性操作引起的疼痛,并降低不良反应发生率。

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