Tašič Muc Blaž, Vella Daniele, Lukač Nejc, Kos Matjaž, Jezeršek Matija
Faculty of Mechanical Engineering, University of Ljubljana, Aškerčeva 6, Ljubljana, Slovenia.
Fotona d.o.o., Stegne 7, Ljubljana, Slovenia.
Biomed Opt Express. 2022 Jun 17;13(7):3993-4006. doi: 10.1364/BOE.460713. eCollection 2022 Jul 1.
A method for amplification of high-intensity pressure waves generated with a multi-pulsed Nd:YAG laser coupled with a black-TiOx optoacoustic lens in the water is presented and characterized. The investigation was focused on determining how the multi-pulsed laser excitation with delays between 50 µs and 400 µs influences the dynamics of the bubbles formed by a laser-induced breakdown on the upper surface of the lens, the acoustic cavitation in the focal region of the lens, and the high-intensity pressure waves generation. A needle hydrophone and a high-speed camera were used to analyze the spatial distribution and time-dependent development of the above-mentioned phenomena. Our results show how different delays ( ) of the laser pulses influence optoacoustic dynamics. When is equal to or greater than the bubble oscillation time, acoustic cavitation cloud size increases 10-fold after the fourth laser pulse, while the pressure amplitude increases by more than 75%. A quasi-deterministic creation of cavitation due to consecutive transient pressure waves is also discussed. This is relevant for localized ablative laser therapy.
本文介绍并表征了一种在水中利用多脉冲Nd:YAG激光与黑色TiOₓ光声透镜耦合产生高强度压力波的方法。研究重点在于确定50微秒至400微秒之间的延迟的多脉冲激光激发如何影响透镜上表面激光诱导击穿形成的气泡动力学、透镜焦区的声空化以及高强度压力波的产生。使用针式水听器和高速摄像机分析上述现象的空间分布和随时间的发展。我们的结果展示了激光脉冲的不同延迟( )如何影响光声动力学。当 等于或大于气泡振荡时间时,在第四个激光脉冲后,声空化云尺寸增大10倍,而压力振幅增加超过75%。还讨论了由于连续瞬态压力波导致的准确定性空化产生。这与局部消融激光治疗相关。