频域光相干断层扫描和光相干断层扫描血管造影在特发性黄斑裂孔干预中的比较。
Comparison of Idiopathic Macular Hole Interventions Using Frequency Domain Optical Coherence Tomography and Optical Coherence Tomography Angiography.
机构信息
Ophthalmology Department, The First Hospital of Nanchang, NanChang, China.
出版信息
Dis Markers. 2022 Aug 13;2022:7749605. doi: 10.1155/2022/7749605. eCollection 2022.
OBJECTIVE
We aimed to determine the efficacy of different idiopathic macular hole treatment methods to improve recovery time and patient outcomes using Frequency Domain Optical Coherence Tomography (SD-OCT) and Optical Coherence Tomography Angiography (OCTA).
METHODS
This retrospective study included patients with idiopathic macular hole who were admitted to our hospital between 1st January 2019 and 31st October 2021. The control group was treated with internal limiting membrane tamponade, and the study group was treated with clamshell therapy. Treatment conditions (internal limiting membrane treatment duration and hole closure rate), best corrected visual acuity (BCVA) before and after surgery, OCTA measurements, and SD-OCT were assessed. The retinal nerve fiber layer (RNFL), retinal ganglion cell layer (GCL), and retinal pigment epithelium (RPE) thicknesses were also analyzed.
RESULTS
The treatment time and hole closure rate of the internal limiting membrane in the study group were higher than those in the control group. The curative effect of the study group was better than that of the control group. The postoperative DCP blood vessel density in both groups was higher than that before operation, and the study group was higher than the control group. The FAZ area and circumference were lower than those before surgery, and the study group was lower than the control group. At 3 months after operation, the thickness of DIOA, nasal temporal RNFL, and GCL were decreased in both groups, and the observed values in the study group were lower than those in the control group. At 3-month follow-up, there was no significant difference in RPE thickness between the two groups.
CONCLUSION
Flip and cover therapy is the most effective treatment. SD-OCT and OCTA provide an objective basis for clinical intervention by comparing the effects of different procedures on the retinal condition of patients.
目的
本研究旨在使用频域光相干断层扫描（SD-OCT）和光相干断层扫描血管造影（OCTA），确定不同特发性黄斑裂孔治疗方法在改善恢复时间和患者预后方面的疗效。
方法
本回顾性研究纳入了 2019 年 1 月 1 日至 2021 年 10 月 31 日期间在我院就诊的特发性黄斑裂孔患者。对照组采用内界膜填塞治疗，观察组采用贝壳状切开术治疗。评估治疗情况（内界膜治疗时间和裂孔闭合率）、手术前后最佳矫正视力（BCVA）、OCTA 测量值和 SD-OCT。还分析了视网膜神经纤维层（RNFL）、视网膜神经节细胞层（GCL）和视网膜色素上皮（RPE）厚度。
结果
观察组内界膜治疗时间和裂孔闭合率均高于对照组，观察组疗效优于对照组。两组术后 DCP 血管密度均高于术前，观察组高于对照组。FAZ 面积和周长均低于术前，观察组低于对照组。术后 3 个月，两组 DIOA、鼻颞侧 RNFL 和 GCL 厚度均降低，观察组观察值低于对照组。术后 3 个月，两组 RPE 厚度无显著差异。
结论
翻转覆盖疗法是最有效的治疗方法。SD-OCT 和 OCTA 通过比较不同手术程序对患者视网膜状况的影响，为临床干预提供了客观依据。
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