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[放疗联合高血糖治疗后肺鳞状细胞癌的形态学测量]

[Morphometry of squamous cell cancer of the lung after radiation therapy combined with hyperglycemia].

作者信息

Furmanchuk A V, Demidchuk Iu E, Khodina T V

出版信息

Med Radiol (Mosk). 1987 Jun;32(6):36-41.

PMID:3600223
Abstract

The authors analysed morphological changes and provided morphological assessment of the parenchyma, stroma, vessels and necrosis in the squamous cell lung carcinoma tissue of 40 patients without preliminary irradiation, 40 patients after gamma-beam therapy and 49 patients after radiotherapy combined with induced hyperglycemia (IH). The total focal dosage was 20 Gy (5 fractions during a week). In 25 patients IH was followed by irradiation and in 24 patients it followed irradiation. Operation was performed on the 7-8th day after therapy was initiated. It was concluded that preoperative gamma-beam therapy followed by IH produced the most noticeable damaging effect on squamous cell lung carcinoma.

摘要

作者分析了40例未经初步照射的鳞状细胞肺癌组织、40例接受伽马射线治疗后的组织以及49例接受放疗联合诱导高血糖(IH)后的组织中的形态学变化,并对实质、间质、血管和坏死情况进行了形态学评估。总局部剂量为20 Gy(一周内分5次)。25例患者先进行IH然后接受照射,24例患者先接受照射然后进行IH。在开始治疗后的第7 - 8天进行手术。得出的结论是,术前先进行伽马射线治疗然后进行IH对鳞状细胞肺癌产生的损伤作用最为明显。

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