Wei Benjamin, Asban Ammar, Xie Rongbing, Sollie Zachary, Deng Luqin, DeLay Thomas K, Swicord William B, Kumar Rajat, Kirklin James K, Donahue James
Department of Cardiothoracic Surgery, University of Alabama at Birmingham School of Medicine, UAB Hospital, Birmingham, Ala.
JTCVS Open. 2021 May 26;7:359-366. doi: 10.1016/j.xjon.2021.05.006. eCollection 2021 Sep.
Urinary retention remains a frequent postoperative complication, associated with patient discomfort and delayed discharge following general thoracic surgery (GTS). We aimed to develop and prospectively validate a predictive model of postoperative urinary retention (POUR) among GTS patients.
We retrospectively developed a predictive model using data from the Society of Thoracic Surgeons GTS Database at our institution. The patient study cohort included adults undergoing elective in-patient surgical procedures without a history of renal failure or Foley catheter on entry to the recovery suite (August 2013 to March 2017). Multivariable logistic regression models identified factors associated with urinary retention, and a nomogram to aid medical decision making was developed. The predictive model was validated in a cohort of GTS patients between April 2017 and November 2018 using receiver operating characteristic (ROC) analysis.
The predictive model was developed from 1484 GTS patients, 284 of whom (19%) experienced postoperative urinary retention within 24 hours of the operation. Risk factors for POUR included older age, male sex, higher preoperative creatinine, chronic obstructive pulmonary disease, primary diagnosis, primary procedure, and use of postoperative patient-controlled analgesia. A logistic nomogram for estimating the risk of POUR was created and validated in 646 patients, 65 of whom (10%) had urinary retention. The ROC curves of development and validation models had similar favorable c-statistics (0.77 vs 0.72; > .05).
Postoperative urinary retention occurs in nearly 20% of patients undergoing major GTS. Using a validated predictive model may help by targeting certain patients with prophylactic measures to prevent this complication.
尿潴留仍然是常见的术后并发症,与患者不适以及普通胸外科手术(GTS)后出院延迟相关。我们旨在开发并前瞻性验证GTS患者术后尿潴留(POUR)的预测模型。
我们使用本机构胸外科医师协会GTS数据库中的数据回顾性开发了一个预测模型模型。患者研究队列包括在进入恢复室时无肾衰竭或留置 Foley 导管史的接受择期住院手术的成年人(2013年8月至2017年3月)。多变量逻辑回归模型确定了与尿潴留相关的因素,并开发了一个有助于医疗决策的列线图。2017年4月至2018年11月期间,使用受试者工作特征(ROC)分析在一组GTS患者中验证了该预测模型。
该预测模型由1484例GTS患者的数据开发而来,其中284例(19%)在术后24小时内发生了术后尿潴留。POUR的危险因素包括年龄较大、男性、术前肌酐水平较高、慢性阻塞性肺疾病、主要诊断、主要手术以及使用术后患者自控镇痛。创建了一个用于估计POUR风险的逻辑列线图,并在646例患者中进行了验证,其中65例(10%)发生了尿潴留。开发模型和验证模型的ROC曲线具有相似的良好c统计量(0.77对0.72;P>.05)。
近20%的接受大型GTS手术的患者会发生术后尿潴留。使用经过验证的预测模型可能有助于针对某些患者采取预防措施以预防这种并发症。